LIFR

Understanding Entity Pages

This page aggregates everything SciDEX knows about LIFR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Page for LIFR - Leukemia Inhibitory Factor Receptor

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graph TD
    LIFR["<b>LIFR</b>"]
    SOX2["SOX2"]
    LIFR -->|"upregulates"| SOX2
    JAK1["JAK1"]
    LIFR -->|"activates"| JAK1
    renal_interstitial_fibrosis{"renal interstitial fibrosis"}
    LIFR -->|"associated with"| renal_interstitial_fibrosis
    gastric_cancer{"gastric cancer"}
    LIFR -->|"associated with"| gastric_cancer
    Leukemia{"Leukemia"}
    LIFR -->|"activates"| Leukemia
    Ms{"Ms"}
    LIFR -->|"activates"| Ms
    Carcinoma{"Carcinoma"}
    LIFR -->|"activates"| Carcinoma
    Cancer{"Cancer"}
    LIFR -->|"activates"| Cancer
    Tumor{"Tumor"}
    LIFR -->|"therapeutic target"| Tumor
    GFAP["GFAP"]
    LIFR -->|"expressed in"| GFAP
    LIF["LIF"]
    LIFR -->|"expressed in"| LIF
    STAT3["STAT3"]
    LIFR -->|"activates"| STAT3
    LIF -->|"binds"| LIFR
    CRLF1["CRLF1"]
    CRLF1 -->|"activates"| LIFR
    STAT3 -->|"activates"| LIFR
    GFAP -->|"expressed in"| LIFR
    LIF -->|"expressed in"| LIFR
    SOX2 -->|"activates"| LIFR
    style LIFR fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0