LIS1

Understanding Entity Pages

This page aggregates everything SciDEX knows about LIS1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

LIS1 is a protein involved in neurodegeneration research. Key relationships include: interacts with, causes, implicated in. Associated with AD, ADH, ALI. Connected to 38 entities in the SciDEX knowledge graph.

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graph TD
    LIS1["<b>LIS1</b>"]
    Ms{"Ms"}
    LIS1 -->|"interacts with"| Ms
    Als{"Als"}
    LIS1 -->|"interacts with"| Als
    LIS1 -->|"associated with"| Als
    Schizophrenia{"Schizophrenia"}
    LIS1 -->|"interacts with"| Schizophrenia
    ALS{"ALS"}
    LIS1 -->|"causes"| ALS
    DAB1["DAB1"]
    LIS1 -->|"interacts with"| DAB1
    PAFAH1B1["PAFAH1B1"]
    LIS1 -->|"associated with"| PAFAH1B1
    CDK5["CDK5"]
    LIS1 -->|"interacts with"| CDK5
    DISC1["DISC1"]
    LIS1 -->|"interacts with"| DISC1
    NEURON["NEURON"]
    LIS1 -->|"causes"| NEURON
    DCX["DCX"]
    LIS1 -->|"causes"| DCX
    DYNEIN["DYNEIN"]
    LIS1 -->|"interacts with"| DYNEIN
    DCX -->|"associated with"| LIS1
    CDK5 -->|"interacts with"| LIS1
    PAFAH1B1 -->|"associated with"| LIS1
    DAB1 -->|"interacts with"| LIS1
    CDK5 -->|"associated with"| LIS1
    DAB1 -->|"associated with"| LIS1
    NDEL1["NDEL1"]
    NDEL1 -->|"interacts with"| LIS1
    CDK5 -->|"causes"| LIS1
    AXON["AXON"]
    AXON -->|"causes"| LIS1
    REELIN["REELIN"]
    REELIN -->|"causes"| LIS1
    AND["AND"]
    AND -->|"interacts with"| LIS1
    NEURON -->|"causes"| LIS1
    style LIS1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0