Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MYELOID CELLS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | MYELOID CELLS |
| Key Genes/Proteins | GFAP, TAU, HDAC3, APOE, TREM2 |
| Related Diseases | OSTEOPOROSIS, FIBROSIS, CANCER |
Knowledge base pages for this entity
graph TD
MYELOID_CELLS["MYELOID CELLS"]
MYELOID_CELLS -->|"involved_in"| Phagocytosis["Phagocytosis"]
MYELOID_CELLS -->|"mediates"| Bone_Resorption["Bone Resorption"]
MYELOID_CELLS -->|"involved_in"| Central_Nervous_System["Central Nervous System"]
MYELOID_CELLS -->|"promotes"| neuronal_debris_clearance["neuronal debris clearance"]
TET2["TET2"] -->|"expressed in"| MYELOID_CELLS
Mitochondria["Mitochondria"] -->|"interacts"| MYELOID_CELLS
Osteolineage_Cells["Osteolineage Cells"] -->|"interacts"| MYELOID_CELLS
TREM2["TREM2"] -->|"expressed in"| MYELOID_CELLS
Regulatory_T_cells["Regulatory T cells"] -->|"inhibits"| MYELOID_CELLS
Inflammatory_Response["Inflammatory Response"] -->|"involved_in"| MYELOID_CELLS| Target | Relation | Type | Str |
|---|---|---|---|
| OSTEOPOROSIS | activates | disease | 0.65 |
| APOE | activates | gene | 0.65 |
| T CELLS | activates | cell_type | 0.65 |
| T CELLS | produces | cell_type | 0.65 |
| FIBROSIS | causes | disease | 0.65 |
| FIBROSIS | activates | disease | 0.65 |
| MACROPHAGES | interacts_with | cell_type | 0.65 |
| STEM CELLS | activates | cell_type | 0.65 |
| OSTEOPOROSIS | implicated_in | disease | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| GFAP | causes | gene | 0.70 |
| TAU | causes | protein | 0.70 |
| HDAC3 | activates | gene | 0.70 |
| MICROGLIA | causes | cell_type | 0.65 |
| TREM2 | causes | gene | 0.65 |
| CANCER | causes | disease | 0.65 |
| MACROPHAGES | causes | cell_type | 0.65 |
| NLRP3 INFLAMMASOME | interacts_with | pathway | 0.65 |
| APOE | causes | gene | 0.65 |
| MAPK | activates | gene | 0.65 |
| ALZHEIMER'S DISEASE | causes | disease | 0.65 |
| NEURONS | causes | cell_type | 0.65 |
| SYK | phosphorylates | gene | 0.65 |
| SYK | causes | gene | 0.65 |
| PHAGOCYTOSIS | causes | phenotype | 0.65 |
| PHAGOCYTOSIS | protects_against | phenotype | 0.65 |
| NEUROFILAMENT LIGHT | associated_with | biomarker | 0.50 |
| NLRP3 INFLAMMASOME | associated_with | pathway | 0.45 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||