POLD1

Understanding Entity Pages

This page aggregates everything SciDEX knows about POLD1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

POLD1 - DNA Polymerase Delta 1 - Catalytic subunit of DNA polymerase delta essential for DNA replication and repair

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graph TD
    POLD1["<b>POLD1</b>"]
    Senescence{"Senescence"}
    POLD1 -->|"interacts with"| Senescence
    Ms{"Ms"}
    POLD1 -->|"interacts with"| Ms
    P53["P53"]
    POLD1 -->|"interacts with"| P53
    POT1["POT1"]
    POLD1 -->|"interacts with"| POT1
    MRE11["MRE11"]
    POLD1 -->|"interacts with"| MRE11
    MUTYH["MUTYH"]
    POLD1 -->|"interacts with"| MUTYH
    SAMHD1["SAMHD1"]
    POLD1 -->|"expressed in"| SAMHD1
    NBS1["NBS1"]
    POLD1 -->|"interacts with"| NBS1
    LMNA["LMNA"]
    POLD1 -->|"expressed in"| LMNA
    WRN["WRN"]
    POLD1 -->|"interacts with"| WRN
    MDM2["MDM2"]
    POLD1 -->|"expressed in"| MDM2
    CTC1["CTC1"]
    POLD1 -->|"expressed in"| CTC1
    TREX1["TREX1"]
    TREX1 -->|"interacts with"| POLD1
    VCP["VCP"]
    VCP -->|"interacts with"| POLD1
    NEIL1["NEIL1"]
    NEIL1 -->|"interacts with"| POLD1
    COMPLEMENT["COMPLEMENT"]
    COMPLEMENT -->|"expressed in"| POLD1
    style POLD1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0