TREX1

Understanding Entity Pages

This page aggregates everything SciDEX knows about TREX1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

TREX1 is a gene implicated in neurodegeneration research. Key relationships include: interacts with, activates, therapeutic target. Associated with Aging, Als, Cancer. Connected to 53 entities in the SciDEX knowledge graph.

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graph TD
    TREX1["<b>TREX1</b>"]
    Als{"Als"}
    TREX1 -->|"regulates"| Als
    Ms{"Ms"}
    TREX1 -->|"regulates"| Ms
    TREX1 -->|"activates"| Ms
    Cancer{"Cancer"}
    TREX1 -->|"activates"| Cancer
    Senescence{"Senescence"}
    TREX1 -->|"interacts with"| Senescence
    TREX1 -->|"interacts with"| Ms
    IKBKG["IKBKG"]
    TREX1 -->|"regulates"| IKBKG
    PSMB8["PSMB8"]
    TREX1 -->|"associated with"| PSMB8
    Nf__b(["Nf-Kappab"])
    TREX1 -->|"regulates"| Nf__b
    CD8["CD8"]
    TREX1 -->|"activates"| CD8
    CANCER["CANCER"]
    TREX1 -->|"activates"| CANCER
    STING["STING"]
    TREX1 -->|"activates"| STING
    SAMHD1["SAMHD1"]
    SAMHD1 -->|"associated with"| TREX1
    style TREX1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0