SAMHD1

Understanding Entity Pages

This page aggregates everything SciDEX knows about SAMHD1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Page for SAMHD1 — SAM and HD Domain Containing Metal Dependent Hydrolase 1

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graph TD
    SAMHD1["<b>SAMHD1</b>"]
    Als{"Als"}
    SAMHD1 -->|"regulates"| Als
    Ms{"Ms"}
    SAMHD1 -->|"regulates"| Ms
    Senescence{"Senescence"}
    SAMHD1 -->|"interacts with"| Senescence
    SAMHD1 -->|"interacts with"| Ms
    TREX1["TREX1"]
    SAMHD1 -->|"associated with"| TREX1
    IKBKG["IKBKG"]
    SAMHD1 -->|"regulates"| IKBKG
    PSMB8["PSMB8"]
    SAMHD1 -->|"associated with"| PSMB8
    Nf__b(["Nf-Kappab"])
    SAMHD1 -->|"regulates"| Nf__b
    NBS1["NBS1"]
    SAMHD1 -->|"interacts with"| NBS1
    LMNA["LMNA"]
    SAMHD1 -->|"expressed in"| LMNA
    WRN["WRN"]
    SAMHD1 -->|"interacts with"| WRN
    MDM2["MDM2"]
    SAMHD1 -->|"expressed in"| MDM2
    TREX1 -->|"interacts with"| SAMHD1
    VCP["VCP"]
    VCP -->|"interacts with"| SAMHD1
    NEIL1["NEIL1"]
    NEIL1 -->|"interacts with"| SAMHD1
    COMPLEMENT["COMPLEMENT"]
    COMPLEMENT -->|"expressed in"| SAMHD1
    POLD1["POLD1"]
    POLD1 -->|"expressed in"| SAMHD1
    P53["P53"]
    P53 -->|"interacts with"| SAMHD1
    POT1["POT1"]
    POT1 -->|"interacts with"| SAMHD1
    MRE11["MRE11"]
    MRE11 -->|"interacts with"| SAMHD1
    MUTYH["MUTYH"]
    MUTYH -->|"interacts with"| SAMHD1
    style SAMHD1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0