TNFRSF21

Understanding Entity Pages

This page aggregates everything SciDEX knows about TNFRSF21: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

TNFRSF21 (DR6) - death receptor in apoptosis and neurodegeneration

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graph TD
    TNFRSF21["<b>TNFRSF21</b>"]
    Ms{"Ms"}
    TNFRSF21 -->|"associated with"| Ms
    Atherosclerosis{"Atherosclerosis"}
    TNFRSF21 -->|"associated with"| Atherosclerosis
    Ferroptosis(["Ferroptosis"])
    TNFRSF21 -->|"associated with"| Ferroptosis
    Necroptosis(["Necroptosis"])
    TNFRSF21 -->|"associated with"| Necroptosis
    neurodegeneration["neurodegeneration"]
    TNFRSF21 -->|"implicated in"| neurodegeneration
    PYCARD["PYCARD"]
    PYCARD -->|"associated with"| TNFRSF21
    HMOX1["HMOX1"]
    HMOX1 -->|"associated with"| TNFRSF21
    CASP1["CASP1"]
    CASP1 -->|"associated with"| TNFRSF21
    NAMPT["NAMPT"]
    NAMPT -->|"associated with"| TNFRSF21
    TNF["TNF"]
    TNF -->|"associated with"| TNFRSF21
    ZFP36["ZFP36"]
    ZFP36 -->|"associated with"| TNFRSF21
    FERROPTOSIS["FERROPTOSIS"]
    FERROPTOSIS -->|"associated with"| TNFRSF21
    NOD2["NOD2"]
    NOD2 -->|"associated with"| TNFRSF21
    IMMUNE_INFILTRATION["IMMUNE INFILTRATION"]
    IMMUNE_INFILTRATION -->|"associated with"| TNFRSF21
    NEAT1["NEAT1"]
    NEAT1 -->|"associated with"| TNFRSF21
    CTSD["CTSD"]
    CTSD -->|"associated with"| TNFRSF21
    style TNFRSF21 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0