DNAJB6

DNAJB6 Protein

Score: 0.453 Price: $0.43 Low Druggability Status: active

HYPOTHESES

PAPERS

KG EDGES

DEBATES

3D Protein Structure

🧬 DNAJB6 — PDB 6U3R Click to expand

Experimental structure from RCSB PDB | Powered by Mol*

Druggability & Clinical Context

Druggability

Low

Score: 0.50

Clinical Stage

Phase I

Target Class

Protein

Safety

0.50

Druggability Analysis

Drug Development0.00

Structural Tractability0.30

Target Class0.50

Safety Profile0.50

Key Metrics

PDB Structures:

Known Drugs:

Approved:

In Clinical Trials:

Therapeutic Areas:

neurodegeneration

Mechanism: Prioritized from 1 SciDEX hypotheses, including: HSP70 Co-chaperone DNAJB6 Universal Cross-Seeding Inhibitor

Known Drugs:

No known drugs targeting this protein

Structural Data:

🧬 3D Protein Structure

🧬 DNAJB6 — PDB 6U3R Click to expand interactive 3D viewer

Experimental structure from RCSB PDB | Powered by Mol* | Rotate: click+drag | Zoom: scroll

Linked Hypotheses (1)

HSP70 Co-chaperone DNAJB6 Universal Cross-Seeding Inhibitor0.420

Linked Experiments (0)

No linked experiments

Scoring Dimensions

Knowledge Graph (20)

activates (4)

DNAJB6 → FUS

DNAJB6 → MYOT

DNAJB6 → NBR1

DNAJB6 → P62

associated with (8)

DNAJB6 → neurodegeneration

DNAJB6 → SQSTM1

DNAJB6 → FLNC

DNAJB6 → NBR1

DNAJB6 → MYOT

...and 3 more

Debate History (0)

No debates yet