gene 940 words KG: CALR
Contents

CALR Gene

🧬 Gene Info
Gene SymbolCALR
Full NameCalreticulin
Chromosome19p13.2
FunctionCalreticulin performs several essential cellular functions:
Subcellular Localizationthe endoplasmic reticulum (ER). Calreticulin is essential for calcium homeostasis, protein quality control, and cellular
Molecular Weight48 kDa
Amino Acids417 aa
PathwaysPyroptosis
UniProt ID[P27797](https://www.uniprot.org/uniprot/P27797)
Ensembl IDENSG00000179218
GeneCardsCALR
Human Protein AtlasCALR
Associated DiseasesALS, dementia, frontotemporal, Ms, neurodegeneration, Tumor
InteractionsAND, APAF1, APOPTOSIS, CANCER, CANX, GSDME
KG Connections70 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

Synaptic Tagging Differential Vulnerability
Score: 0.00

Knowledge Graph (12 edges)

WLS interacts_with CALR
BCL2 regulates CALR
CALR activates GSDME
CALR associated_with S100A6
CALR expressed_in AKT
CALR associated_with PRDX5
CALR associated_with CTSD
CALR regulates BCL2
CALR regulates HSP70
CALR regulates HSPA1A

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