apaf1

Understanding Entity Pages

This page aggregates everything SciDEX knows about apaf1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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graph TD
    APAF1["APAF1"]
    APAF1 -->|"participates in"| apoptosis["apoptosis"]
    APAF1 -->|"activates"| caspase_9["caspase-9"]
    APAF1 -->|"activates"| caspase_3["caspase-3"]
    APAF1 -->|"participates in"| axon_degeneration["axon_degeneration"]
    APAF1 -->|"implicated in"| neurodegenerative_diseases["neurodegenerative_diseases"]
    APAF1 -.biomarker for.-> Melanoma["Melanoma"]
    APAF1 -->|"activates"| Inflammation["Inflammation"]
    APAF1 -->|"activates"| Als["Als"]
    TCTP["TCTP"] -->|"binds"| APAF1
    TP53["TP53"] -->|"participates in"| APAF1
    CYTC["CYTC"] -->|"participates in"| APAF1
    STING["STING"] -->|"regulates"| APAF1
    GENES["GENES"] -->|"activates"| APAF1
    NRF2["NRF2"] -->|"regulates"| APAF1
    CYLD["CYLD"] -->|"activates"| APAF1
    AMPK["AMPK"] -->|"activates"| APAF1