| Gene Symbol | CASP8 |
| Full Name | Caspase 8 |
| Chromosome | 2q33 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 20 kDa |
| Amino Acids | 80 aa |
| Pathways | Akt, Nf-Κb, Pi3K, Toll-Like Receptor |
| UniProt ID | [Q14790](https://www.uniprot.org/uniprot/Q14790) |
| Ensembl ID | ENSG00000164040 |
| GeneCards | CASP8 |
| Human Protein Atlas | CASP8 |
| CASP8a (CASP8) | Full-length canonical isoform |
| CASP8b | Alternative splice form with unique N-terminus |
| CASP8L | Long isoform with extended prodomain |
| Associated Diseases | Als, Autoimmune, Ms, Rheumatoid Arthritis |
| Known Drugs/Compounds | natural products |
| Interactions | Actin, AKT1, AND, APOPTOSIS, CANCER, CASP3 |
| KG Connections | 175 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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