clinical 842 words KG: PD
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Bacillus Subtilis for Parkinson Disease (NCT06487975)

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Related Hypotheses (15)

APOE Isoform Expression Across Glial Subtypes
Score: 0.74
Smartphone-Detected Motor Variability Correction
Score: 0.74
PARP1 Inhibition Therapy
Score: 0.74
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
Sphingomyelin Synthase Activators for Raft Remodeling
Score: 0.69
Ganglioside Rebalancing Therapy
Score: 0.69
Arginine Methylation Enhancement Therapy
Score: 0.65
Microbial Inflammasome Priming Prevention
Score: 0.65
Mitochondrial Calcium Buffering Enhancement via MCU Modulati
Score: 0.65
Sphingolipid Metabolism Reprogramming
Score: 0.62
Digital Twin-Guided Metabolic Reprogramming
Score: 0.55
Gut Barrier Permeability-α-Synuclein Axis Modulation
Score: 0.53
Piezoelectric Nanochannel BBB Disruption
Score: 0.52
Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.51
Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.48

Related Analyses (11)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
GBA-Synuclein Loop Therapeutics for PD
neurodegeneration · completed
Gut-Brain Axis Therapeutics for AD
neurodegeneration · completed
TREM2 agonism vs antagonism in DAM microglia
neurodegeneration · completed
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · completed

Related Experiments (15)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40
SCFA-Mediated Neuroinflammation in Alzheimer's Disease
clinical · proposed · Score: 0.40
RBG treatment in ApoE-/- atherosclerosis mouse model
validation · proposed · Score: 0.90
Leukocyte gene expression analysis in COVID-19 patients
exploratory · proposed · Score: 0.90
Longitudinal TLR2 reporter gene study in α-synuclein mice
validation · proposed · Score: 0.90

See Also (11)

GBA1 (Redirect)
redirect · KG edge: causes
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: implicated_in
ABCB1 (MDR1) - ATP Binding Cassette Subfamily B Member
gene · KG edge: implicated_in
APOB Gene
gene · KG edge: implicated_in
CNTNAP4 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

PD causes NEURODEGENERATION
PD causes DOPAMINERGIC_NEURONS
PD causes neurodegeneration
NEUROTROPHINS treats PD
AGE associated_with PD
SNCA causes PD
LRRK2 causes PD
GBA1 causes PD
PRKN causes PD
PINK1 causes PD

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