concept

FANCI

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about FANCI: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

28Connections
0Hypotheses
0Analyses
20Outgoing
8Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameFANCI
Key Genes/ProteinsP53, PPM1D, FANCE, AIM2, ATR, ATM
Related DiseasesAls, Senescence
Related PathwaysRAS signaling pathway, Inflammasome, Er Stress, Apoptosis

Wiki Pages (20)

Knowledge base pages for this entity

Oligodendrocytes

cell · 4838 words

Remyelination in Neurodegeneration

mechanism · 3377 words

FA2H Gene

gene · 3327 words

Demyelination

mechanism · 3212 words

FANCF Gene

gene · 2646 words

Pathway Diagram

graph TD
    FANCI["FANCI"]
    FANCI -->|"inhibits"| RAS_signaling_pathway["RAS signaling pathway"]
    FANCI -->|"contributes to"| Als["Als"]
    FANCI -->|"contributes to"| Senescence["Senescence"]
    FANCI -->|"interacts"| P53["P53"]
    FANCI -->|"interacts"| PPM1D["PPM1D"]
    FANCI -->|"interacts"| FANCE["FANCE"]
    FANCI -->|"contributes to"| AIM2["AIM2"]
    FANCI -->|"interacts"| ATR["ATR"]
    FANCC["FANCC"] -->|"interacts"| FANCI
    APOPTOSIS["APOPTOSIS"] -->|"contributes to"| FANCI
    ATM["ATM"] -->|"interacts"| FANCI
    FANCA["FANCA"] -->|"interacts"| FANCI
    DNA["DNA"] -->|"interacts"| FANCI
    CGAS_STING["CGAS-STING"] -->|"contributes to"| FANCI

Outgoing (20)

TargetRelationTypeStr
RAS signaling pathwayinhibitspathway0.85
Alscontributes_todisease0.65
Senescencecontributes_todisease0.65
P53interacts_withgene0.60
PPM1Dinteracts_withgene0.60

Incoming (8)

SourceRelationTypeStr
FANCCinteracts_withgene0.60
APOPTOSIScontributes_togene0.60
ATMinteracts_withgene0.60
FANCAinteracts_withgene0.60
DNAinteracts_withgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found