| Gene Symbol | KLF4 |
| Full Name | Kruppel-Like Factor 4 |
| Chromosome | 9q31.2 |
| Protein Type | Transcription Factor |
| Function | Cell cycle control: Represses proliferation genes (c-Myc, cyclin D1) while activating cell cycle inhibitors (p21, p27) |
| Primary Expression | High in brain, GI tract, endothelial cells |
| Amino Acids | 483 aa |
| Pathways | Akt, Amyloid, Epigenetic, Neurogenesis, Nf-Kb |
| UniProt ID | O43474 |
| NCBI Gene ID | 9312 |
| Ensembl ID | ENSG00000109576 |
| OMIM | 602253 |
| GeneCards | KLF4 |
| Human Protein Atlas | KLF4 |
| Associated Diseases | aging, Atherosclerosis, Inflammation, Ms, neurodegeneration, Senescence |
| Interactions | AND, APOPTOSIS, App, ARG1, ATG7, ATP2A3 |
| SciDEX Hypotheses | KLF4-Mediated Transcriptional Repression of P2RY12 Temporal Chromatin Oscillator Reset Therapy |
| KG Connections | 246 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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