SORAFENIB

Understanding Entity Pages

This page aggregates everything SciDEX knows about SORAFENIB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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graph TD
    SORAFENIB["SORAFENIB"]
    SORAFENIB -->|"activates"| ferroptosis["ferroptosis"]
    SORAFENIB -->|"inhibits"| SYSTEM_XC_["SYSTEM XC-"]
    SORAFENIB -->|"treats"| Liver_Fibrosis["Liver Fibrosis"]
    SORAFENIB -->|"inhibits"| Extracellular_Matrix_Accumulat["Extracellular Matrix Accumulation"]
    SORAFENIB -->|"treats"| liver_fibrosis["liver_fibrosis"]
    SORAFENIB -->|"upregulates"| IL12A["IL12A"]
    SORAFENIB -->|"regulates"| HIF1A["HIF1A"]
    SORAFENIB -->|"regulates"| STEM_CELLS["STEM CELLS"]
    GPAT3["GPAT3"] -->|"targets"| SORAFENIB
    SLC7A11["SLC7A11"] -->|"regulates"| SORAFENIB
    NRF2["NRF2"] -->|"regulates"| SORAFENIB
    GPX4["GPX4"] -->|"regulates"| SORAFENIB
    FERROPTOSIS["FERROPTOSIS"] -->|"regulates"| SORAFENIB
    FIBROSIS["FIBROSIS"] -->|"regulates"| SORAFENIB
    ACSL4["ACSL4"] -->|"regulates"| SORAFENIB
    BECN1["BECN1"] -->|"activates"| SORAFENIB