gene 502 words KG: GATA3
Contents

GATA3 - GATA Binding Protein 3

🧬 Gene Info
Gene SymbolGATA3
Full NameGATA Binding Protein 3
AliasesPage for GATA3
Protein TypeTranscription Factor
FunctionGATA3 plays diverse roles in development and adult neural function
Primary Expressionhypothalamic neurons and regulates neuroendocrine functions
PathwaysDifferentiation, Hippo Pathway
Ensembl IDENSG00000107485
GeneCardsGATA3
Human Protein AtlasGATA3
Associated DiseasesAls, Alzheimer, Asthma, Autoimmune, Cancer, Carcinoma
InteractionsAND, AQP3, AQP4, FOXP3, GATA2, GENES
KG Connections105 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (10)

Reelin-Mediated Cytoskeletal Stabilization Protocol
Score: 0.69
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
SASP-Driven Aquaporin-4 Dysregulation
Score: 0.78
Aquaporin-4 Polarization Rescue
Score: 0.73
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73
Optogenetic Microglial Deactivation via Engineered Inhibitor
Score: 0.66
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Fractalkine Axis Amplification via CX3CR1 Positive Allosteri
Score: 0.56
Glymphatic System-Enhanced Antibody Clearance Reversal
Score: 0.54

Related Analyses (7)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · completed
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

See Also (13)

AQP4 (Aquaporin-4 Gene)
gene · KG edge: activates
ATF6 - Activating Transcription Factor 6
gene · KG edge: associated_with
BCL2 Gene
gene · KG edge: expressed_in
BMP7 Gene (Bone Morphogenetic Protein 7)
gene · KG edge: associated_with
CCL20 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

AQP4 activates GATA3
GATA3 activates GATA2
GATA3 regulates NFATC1
GATA3 activates MST1
TGFB1 regulates GATA3
TGFBR2 regulates GATA3
RORA associated_with GATA3
BMP7 associated_with GATA3
CX3CR1 associated_with GATA3
AHR associated_with GATA3

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