| Gene Symbol | MIEF2 |
| Full Name | Mitochondrial Elongation Factor 2 (MiD50) |
| Chromosome | 17p13.1 |
| Function | encodes a critical mitochondrial outer membrane protein that plays essential roles in regulating mitochondrial dynamics. |
| Molecular Weight | 50 kDa |
| Pathways | Autophagy, Mitophagy |
| UniProt ID | [Q8N5Z0](https://www.uniprot.org/uniprot/Q8N5Z0) |
| Ensembl ID | ENSG00000146070 |
| GeneCards | MIEF2 |
| Human Protein Atlas | MIEF2 |
| Transmembrane domain | Anchors protein in the outer membrane |
| Cytosolic domain | Interacts with Drp1 and other proteins |
| Flexible linker region | Connects membrane and cytosolic domains |
| PINK1 phosphorylation | Upon mitochondrial damage, PINK1 accumulates on the outer membrane |
| Parkin recruitment | PINK1 phosphorylates ubiquitin and Parkin, activating it |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| KG Connections | 29 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |