gene 663 words KG: NFKBIE 2026-03-30
kind:genesection:genesstate:publishedtopic:neuroinflammationtopic:nf-kappa-b
Contents

NFKBIE Gene

🧬 Gene Info
Gene SymbolNFKBIE
Full NameNFKB Inhibitor Epsilon
Chromosome2p13.2
Functionmodulate NF-κB activity in Alzheimer's
Primary ExpressionUbiquitous
Amino Acids399 aa
PathwaysNFKB, nfkb, NF-κB, NF-κB signaling
UniProt IDO00221
NCBI Gene ID4794
GeneCardsNFKBIE
Human Protein AtlasNFKBIE
Associated Diseasesneurodegeneration
InteractionsCDKN2A, SMARCA4, TP53, KMT2D, NSD2, NOTCH2
KG Connections16 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (2)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (14)

Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: therapeutic_target
Packard Center for ALS Research
institution · KG edge: therapeutic_target
TP53 Gene
gene · KG edge: interacts_with
SOX11 — SRY-Box Transcription Factor 11
gene · KG edge: therapeutic_target
SMARCA4
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

NFKBIE interacts_with CDKN2A
NFKBIE interacts_with SMARCA4
NFKBIE therapeutic_target Aging
NFKBIE therapeutic_target Als
NFKBIE therapeutic_target Lymphoma
NFKBIE therapeutic_target Epigenetic
NFKBIE interacts_with Notch
CD19 therapeutic_target NFKBIE
TP53 interacts_with NFKBIE
SOX11 therapeutic_target NFKBIE