gene 937 words KG: CD19 2026-03-31
kind:genesection:genesstate:published
Contents

CD19 Gene

🧬 Gene Info
Gene SymbolCD19
Full NameCD19 Molecule
Chromosome16p11.2
Functionis a member of the immunoglobulin superfamily and functions as a critical signaling co-receptor on the surface of B cells.
PathwaysPI3K, PI3K Pathway, NF-κB
UniProt IDP15391
NCBI Gene ID933
Ensembl IDENSG00000177455
OMIM107741
GeneCardsCD19
Human Protein AtlasCD19
Associated DiseasesALS, Autoimmune, Cancer, Inflammation, Lymphoma, Multiple Sclerosis
Known Drugs/CompoundsInebilizumab-Cdon
InteractionsEEF2, CCL5, TNF, TLR7, CAT, ACTB
KG Connections181 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (9)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
SASP-Driven Aquaporin-4 Dysregulation
Score: 0.59
Glymphatic System-Enhanced Antibody Clearance Reversal
Score: 0.54
Aquaporin-4 Polarization Rescue
Score: 0.51
Endothelial Glycocalyx Regeneration via Syndecan-1 Upregulat
Score: 0.50

Related Analyses (7)

4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived

See Also (12)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: regulates
Packard Center for ALS Research
institution · KG edge: therapeutic_target
C5
gene · KG edge: inhibits
BECN1 Gene
gene · KG edge: regulates
BCL2 Gene
gene · KG edge: therapeutic_target

Knowledge Graph (12 edges)

CD19 therapeutic_target NEUROMYELITIS OPTICA SPECTRUM DISORDER
CD19 regulates BECN1
CD19 therapeutic_target CD47
CD19 therapeutic_target GBM
CD19 interacts_with EEF2
CD19 interacts_with CCL5
CD19 interacts_with TNF
CD19 interacts_with TLR7
CD19 interacts_with CAT
CD19 interacts_with ACTB