| Gene Symbol | PGC1A |
| Full Name | PPARG Coactivator 1 Alpha |
| Chromosome | 4p15.1 |
| Target Class | Protein |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Mechanism of Action | Prioritized from 1 SciDEX hypotheses, including: Metabolic Reprogramming via Coordinated Multi-Gene CRISPR Circuits |
| Primary Expression | neurons, astrocytes, and oligodendrocytes [18] - Regulation: Highly responsive to environmental and h |
| Druggability | Undruggable (0.23) |
| Molecular Weight | 91 kDa |
| Pathways | AMPK, MAPK pathway |
| UniProt ID | Q9UBX3 |
| NCBI Gene ID | 10887 |
| Ensembl ID | ENSG00000100739 |
| GeneCards | PGC1A |
| Human Protein Atlas | PGC1A |
| Associated Diseases | Aging, Als, Breast Cancer, Cancer, Huntington's disease, neurodegeneration |
| Interactions | ACETYL-COA, AGING, AMPK, AND, APOE, ATP |
| SciDEX Target | View Target Profile |
| KG Connections | 203 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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