| Gene Symbol | PRKAA2 |
| Full Name | Protein Kinase AMP-Activated Catalytic Subunit Alpha 2 |
| Aliases | AMP-Activated Protein Kinase Catalytic Subunit Alpha 2 |
| Chromosome | 1p32.2 |
| Protein Type | Serine/Threonine Kinase |
| Function | is a convergent pathomechanism across major neurodegenerative diseases, making PRKAA2 a high-priority therapeutic target. |
| Primary Expression | oligodendrocytes |
| Amino Acids | 552 aa |
| Exons | 12 |
| Pathways | Autophagy, autophagy pathway, complement cascade, oxidative stress response, phagocytosis |
| Ensembl ID | ENSG00000162409 |
| GeneCards | PRKAA2 |
| Human Protein Atlas | PRKAA2 |
| Associated Diseases | Alzheimer Disease, neurodegeneration |
| Known Drugs/Compounds | AICAR, metformin, Metformin, rapamycin |
| Interactions | ACOX1, ADIPOQ, AMPK, App, ATG, AUTOPHAGY |
| KG Connections | 231 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!