| Gene Symbol | PRMT5 |
| Full Name | Protein Arginine Methyltransferase 5 |
| Aliases | SKB1, JBP1, IBP72, HRMT1L5 |
| Chromosome | 14q11.2 |
| Protein Type | Transferase |
| Function | encodes a type II protein arginine methyltransferase that catalyzes symmetric dimethylation of arginine residues on histones and non-histone substrates. |
| Gene Type | Protein-coding |
| Pathways | Stem Cell |
| UniProt ID | O14744 |
| Ensembl ID | ENSG00000100462 |
| OMIM | 604045 |
| GeneCards | PRMT5 |
| Human Protein Atlas | PRMT5 |
| HGNC | 20601 |
| Entrez Gene | 10419 |
| Associated Diseases | AD, ALS, ARM, BREAST CANCER, Cancer |
| Known Drugs/Compounds | PARP inhibitor |
| Interactions | PRMT1, STAT3, SRC, RHOT1, RB1, CANCER |
| KG Connections | 170 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |