gene 1,291 words KG: QSOX1 2026-03-24
kind:genesection:genesstate:published
Contents

QSOX1 Gene

🧬 Gene Info
Gene SymbolQSOX1
Full NameQuiescin Q6 Sulfhydryl Oxidase 1
AliasesQSOX, Q6, QSCN6
Chromosome1q24.2
Protein FamilySulfhydryl oxidase, ERV/QUSOX family
Protein TypeEnzyme
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionvarious tissues, with high expression in the brain, particularly in neurons and glial cells[@thorpe2002]
Molecular Weight67 kDa
Amino Acids609 aa
PathwaysMapk
OMIM603180
GeneCardsQSOX1
Human Protein AtlasQSOX1
ProteinQSOX1
Associated Diseasesneurodegeneration
InteractionsLAMB2, WNT4, LGALS1, JAK2, GNB4, HSP90B1
KG Connections28 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (5)

Transcriptional Autophagy-Lysosome Coupling
Score: 0.66
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
HSP90-Tau Disaggregation Complex Enhancement
Score: 0.44

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Wnt Signaling in Neurodegeneration
mechanism · KG edge: activates
MAPK Signaling Pathways in Neurodegeneration
mechanism · KG edge: regulates
Packard Center for ALS Research
institution · KG edge: activates
WNT4 Gene
gene · KG edge: activates
PRKACB — Protein Kinase cAMP-Activated Catalytic Subuni
gene · KG edge: activates

Knowledge Graph (12 edges)

QSOX1 activates LAMB2
QSOX1 activates WNT4
QSOX1 activates LGALS1
QSOX1 activates JAK2
QSOX1 regulates AKT
QSOX1 activates GNB4
QSOX1 regulates AXON
QSOX1 regulates CANCER
QSOX1 regulates Melanoma
QSOX1 regulates Diabetes