gene 2,088 words KG: TXNIP
Contents

TXNIP Gene

🧬 Gene Info
Gene SymbolTXNIP
Chromosome1q21.1
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionvirtually all tissues, with particularly high expression in brain (especially hippocampus, hypothalamus, and cortex), he
Molecular Weight46 kDa
Amino Acids397 aa
Exons9
PathwaysAmyloid, Er Stress, Inflammasome, Nf-Κb
NCBI Gene ID10628
GeneCardsTXNIP
Human Protein AtlasTXNIP
Thioredoxin (TRX1/2)Direct binding
Thioredoxin ReductaseIndirect
PeroxiredoxinsIndirect
NLRP3Direct binding
Associated Diseasesneuroinflammation
InteractionsNRF2, NLRP3, SQSTM1, MAP1LC3B, HSPA1A, CXCR4
KG Connections258 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph