gene 1,662 words KG: HNF4A 2026-03-27
kind:genesection:genesstate:publishedtopic:alzheimerstopic:parkinsons
Contents

HNF4A - Hepatocyte Nuclear Factor 4 Alpha

🧬 Gene Info
Gene SymbolHNF4A
Full NameHepatocyte Nuclear Factor 4 Alpha
Chromosome20q13.12
Protein TypeReceptor
Functionis a nuclear receptor transcription factor that plays essential roles in metabolic regulation, organ development, and cellular homeostasis.
Primary Expressionneurons across multiple regions
Amino Acids465 aa
Exons13
PathwaysAmyloid
UniProt ID[P41235](https://www.uniprot.org/uniprot/P41235)
Ensembl IDENSG00000101076
GeneCardsHNF4A
Human Protein AtlasHNF4A
Promoter P1Drives expression in liver, pancreas, and kidney
Promoter P2Active in brain, muscle, and other tissues
Associated DiseasesHepatitis
InteractionsIL6R, AKT, AXIN1, MYC, YWHAZ, TXNIP
KG Connections100 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph