| Gene Symbol | BCL2 |
| Aliases | B-cell lymphoma 2 |
| Protein Family | BCL-2 family (anti-apoptotic subfamily) |
| Function | Direct BAX/BAK inhibition |
| Subcellular Localization | ** Mitochondrial outer membrane, ER, nuclear envelope |
| Molecular Weight | 26 kDa |
| Pathways | Akt, Apoptosis, Autophagy, BMP signaling, Bh4 Domain |
| UniProt ID | P10415 |
| GeneCards | BCL2 |
| Human Protein Atlas | BCL2 |
| Associated Diseases | AD, ALI, ALS, AUTOPHAGY, Aging |
| Known Drugs/Compounds | RAPAMYCIN, BERBERINE, R-PE, cadmium, magnolol, Tirzepatide |
| Interactions | LMNA, STING1, TAX1BP1, ATM, SNCAIP, RB1CC1 |
| KG Connections | 2784 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |