| Gene Symbol | CANX |
| Full Name | Calnexin |
| Protein Type | Chaperone |
| Function | is a calcium-binding chaperone protein located in the endoplasmic reticulum (ER) membrane that plays a critical role in protein folding, quality control, and calcium homeostasis. |
| Primary Expression | Hippocampus |
| Pathways | Apoptosis, Mitophagy, Autophagy, Mapk, Cell Cycle |
| GeneCards | CANX |
| Human Protein Atlas | CANX |
| ERp57 | A thiol-disulfide oxidoreductase that works with calnexin to promote proper disulfide bond formation |
| ERp72 | Another ER-resident chaperone involved in protein folding |
| Bip/GRP78 | The major ER chaperone that binds to misfolded proteins |
| Calreticulin | The soluble counterpart of calnexin in the ER lumen |
| Associated Diseases | AD, ALI, ALS, Alzheimer, Parkinson |
| Interactions | LGALS3, CALCOCO2, G3BP1, PEX3, SQSTM1, BCL2 |
| KG Connections | 554 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |