protein 937 words KG: MAP1B
Contents

MAP1B Protein

🔬 Protein Info
Gene SymbolMAP1B
Full NameMicrotubule-Associated Protein 1B
Chromosome5q13.2
Protein FamilyMAP1 family
Protein TypeProtein
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressiondeveloping neurons
Subcellular LocalizationAxons, growth cones, synaptic terminals, dendrites
Molecular Weight~300 kDa (heavy chain), ~30 kDa (light chains)
Amino Acids2700 aa
PathwaysAutophagy, NF-kB signaling
UniProt IDP46821
GeneCardsMAP1B
Human Protein AtlasMAP1B
SubunitsMAP1B heavy chain (MAP1B-HC) and light chains (MAP1B-LC1, LC2, LC3)
Associated DiseasesAD, ALI, Als, AMI, NMO, RA
InteractionsAUTOPHAGY, LC3, MAP1A, MAP2, MAP6, Proteins
KG Connections60 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

UniProtWikipedia

Related Hypotheses (1)

hnRNP A2/B1 Staufen2-Mediated Axonal RNA Granule Transport F
Score: 0.85

Knowledge Graph (12 edges)

MAP2 interacts_with MAP1B
MAP1B interacts_with MAP6
MAP1B interacts_with MAP2
MAP1B regulates GABARAP
MAP1B implicated_in NMO
MAP1B interacts_with UBIQUITIN
MAP1B associated_with NBR1
MAP1B interacts_with LC3
MAP1B interacts_with TAU
MAP6 interacts_with MAP1B

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