| Gene Symbol | PRKACB |
| Full Name | Protein Kinase cAMP-Activated Catalytic Subunit Beta |
| Chromosome | 1p31.1 |
| Function | PKA catalytic subunit β (PKA-Cβ) catalyzes phosphate transfer: - cAMP binds to regulatory subunits, releasing catalytic subunits - Free catalytic subunits phosphorylate target proteins on serine/threo |
| Molecular Weight | 40.6 kDa |
| Amino Acids | 361 aa |
| Pathways | Mapk |
| UniProt ID | P22694 |
| Ensembl ID | ENSG00000142831 |
| GeneCards | PRKACB |
| Human Protein Atlas | PRKACB |
| Synaptic plasticity | Phosphorylation of AMPA receptor subunits |
| Gene transcription | CREB phosphorylation and activation |
| Ion channel modulation | Regulation of NMDA, AMPA, and voltage-gated channels |
| Cytoskeletal dynamics | Microtubule-associated proteins |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Interactions | CDK1, EGFR, ERBB2, FOXO1, GENES, GNB4 |
| KG Connections | 56 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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