protein 764 words KG: GRIK4
Contents

GRIK4 Gene

🔬 Protein Info
Gene SymbolGRIK4
Full NameGlutamate Ionotropic Kainate Type Subunit 4
AliasesPage for GRIK4, Page for GRIK4 Protein
Chromosome21q21.3
Protein TypeReceptor
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight100 kDa
Amino Acids906 aa
Exons16
UniProt IDQ16479
NCBI Gene ID2899
Ensembl IDENSG00000160225
OMIM604153
GeneCardsGRIK4
Human Protein AtlasGRIK4
Associated DiseasesAlzheimer, Autism, Bipolar, Cancer, Depression, Inflammation
InteractionsCACNA1B, CACNA1H, DRD1, DRD2, GABRA1, GABRB2
KG Connections87 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

UniProtWikipedia

Related Hypotheses (5)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
CYP46A1 Overexpression Gene Therapy
Score: 0.77
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.67
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (10)

Genes
index · KG edge: associated_with
BDNF Gene
gene · KG edge: associated_with
CACNA1B Gene
gene · KG edge: interacts_with
CACNA1H Gene
gene · KG edge: associated_with
DRD1 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

GRIK4 associated_with TRD
BDNF associated_with GRIK4
GRIK4 associated_with SLC6A4
GRIK4 associated_with KCNK2
SLC6A4 associated_with GRIK4
KCNK2 associated_with GRIK4
GRIK4 associated_with BDNF
GABRB2 associated_with GRIK4
SLC1A1 associated_with GRIK4
SLC6A2 associated_with GRIK4

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