protein 587 words KG: GRIN1 2026-03-23
kind:proteinsection:proteinsstate:published
Contents

GRIN1 Protein

🔬 Protein Info
Gene SymbolGRIN1
Full NameGRIN1
Chromosome9q34.1
Protein TypeProtein
Functionof 938 amino acids
Molecular Weight105 kDa
Amino Acids938 aa
Exons21
PathwaysSRC-mediated Phosphorylation
UniProt IDSearch UniProt
GeneCardsGRIN1
Human Protein AtlasGRIN1
Associated DiseasesHuntington's disease, Memory Impairment
Known Drugs/CompoundsD-glutamate
InteractionsHCRTR1, DRD2, HRH3, HCRTR2, ADRA1B, DRD1
KG Connections48 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (6)

ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro
Score: 0.66
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Orexin-Microglia Modulation Therapy
Score: 0.49
Trinucleotide Repeat Sequestration via CRISPR-Guided RNA Tar
Score: 0.48
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42

Related Analyses (7)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Packard Center for ALS Research
institution · KG edge: activates
HCRTR1
gene · KG edge: activates
GRIA1 Gene
gene · KG edge: activates
GRB2 — Growth Factor Receptor Bound Protein 2
gene · KG edge: therapeutic_target
DRD2 Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

GRIN1 provides_data_for ds-83b31ef18d49
GRIN1 activates HCRTR1
GRIN1 therapeutic_target ADAM10
GRIN1 associated_with Memory Impairment
GRIN1 causes HTT
GRIN1 causes MBNL1
GRIN1 interacts_with D-glutamate
GRIN1 mediates calcium signaling
GRIN1 associated_with HCN1
GRIN1 associated_with KMT2D