protein 591 words KG: LC3BPROTEIN 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

LC3B Protein

🔬 Protein Info
Gene SymbolLC3B
AliasesLC3BPROTEIN
Chromosome16q24.2.
Subcellular Localization</strong></td><td>Cytoplasm, Autophagosome membrane</td></tr>
PathwaysAmyloid Beta Clearance
GeneCardsLC3B
Human Protein AtlasLC3B
Associated DiseasesAD, ALI, ALS, Aging, Alzheimer
Known Drugs/Compoundscurcumin, rapamycin
InteractionsDRP1, SESN2, RB1, ATG, BCL2L13, SNCAIP
KG Connections1779 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (13)

SASP-Mediated Complement Cascade Amplification
Score: 0.70
Transcriptional Autophagy-Lysosome Coupling
Score: 0.66
Circadian Clock-Autophagy Synchronization
Score: 0.55
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.47

Related Analyses (11)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived

Related Experiments (7)

Proposed experiment from debate on Synaptic pruning by micro
falsification · proposed · Score: 0.40
Proposed experiment from debate on Senolytics targeting p16/
falsification · proposed · Score: 0.40
Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?
clinical · proposed · Score: 0.40
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40
Mixed Pathology Effects on Parkinson's Disease Progression a
clinical · proposed · Score: 0.40

See Also (15)

Wnt/β-Catenin Signaling Pathway in Neurodegeneration
mechanism · Pages share 6 hypotheses
WNK1-Bilirubin Signaling in Neuroinflammation and Neuro
mechanism · Pages share 6 hypotheses
vip-vasoactive-intestinal-peptide-signaling-neurodegene
mechanism · Pages share 6 hypotheses
VEGF Signaling and Cerebral Angiogenesis in Neurodegene
mechanism · Pages share 6 hypotheses
Vagus Nerve Pathway in Neurodegeneration
mechanism · Pages share 6 hypotheses