Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SMOC2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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graph TD
SMOC2["SMOC2"]
SMOC2 -->|"contributes to"| VEGFA["VEGFA"]
SMOC2 -->|"contributes to"| AND["AND"]
SMOC2 -->|"contributes to"| VEGFB["VEGFB"]
SMOC2 -->|"contributes to"| ACHE["ACHE"]
SMOC2 -->|"contributes to"| Endothelial["Endothelial"]
SMOC2 -->|"contributes to"| Vegf["Vegf"]
DES["DES"] -->|"co_expressed_with"| SMOC2
ACHE -->|"contributes to"| SMOC2
VEGFB -->|"contributes to"| SMOC2
VEGFA -->|"contributes to"| SMOC2| Target | Relation | Type | Str |
|---|---|---|---|
| Als | associated_with | disease | 0.65 |
| Alzheimer | associated_with | disease | 0.65 |
| ALS | associated_with | disease | 0.65 |
| CTSF | associated_with | gene | 0.60 |
| AND | contributes_to | gene | 0.60 |
| ALZHEIMER'S DISEASE | associated_with | gene | 0.60 |
| VEGFB | contributes_to | gene | 0.60 |
| Myelination | associated_with | pathway | 0.60 |
| Immune Response | associated_with | pathway | 0.60 |
| ACHE | contributes_to | gene | 0.60 |
| CLU | associated_with | gene | 0.60 |
| SMPD1 | associated_with | gene | 0.60 |
| CFB | associated_with | gene | 0.60 |
| Endothelial | contributes_to | cell_type | 0.60 |
| ALZHEIMER | associated_with | gene | 0.60 |
| blood-brain barrier | expressed_in | brain_region | 0.60 |
| BIN1 | associated_with | gene | 0.60 |
| VEGFA | contributes_to | gene | 0.60 |
| APOE | associated_with | gene | 0.60 |
| Vegf | contributes_to | protein | 0.60 |
| VEGFA | implicated_in | gene | 0.60 |
| VEGFB | implicated_in | gene | 0.60 |
| blood-brain barrier | participates_in | pathway | 0.60 |
| endothelial cells | expressed_in | cell_type | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| DES | co_expressed_with | gene | 0.80 |
| VEGFA | contributes_to | gene | 0.60 |
| ACHE | implicated_in | gene | 0.60 |
| CFB | associated_with | gene | 0.60 |
| SMPD1 | associated_with | gene | 0.60 |
| APOE | associated_with | gene | 0.60 |
| CLU | associated_with | gene | 0.60 |
| ACHE | contributes_to | gene | 0.60 |
| ALZHEIMER DISEASE | associated_with | gene | 0.60 |
| VEGFB | contributes_to | gene | 0.60 |
| ALZHEIMER | associated_with | gene | 0.60 |
| BIN1 | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity