VEGF

Understanding Entity Pages

This page aggregates everything SciDEX knows about VEGF: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Page for VEGF (Vascular Endothelial Growth Factor)

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flowchart TD
    BMAL1["BMAL1<br/>Circadian Regulator"]
    HIF1A["HIF1A<br/>Hypoxia-Inducible Factor"]
    VEGF["VEGF<br/>Vascular Endothelial<br/>Growth Factor"]
    Angiogenesis["Angiogenesis<br/>Blood Vessel Formation"]
    bevacizumab["Bevacizumab<br/>Anti-VEGF Therapy"]
    
    ALS["ALS<br/>Amyotrophic Lateral<br/>Sclerosis"]
    MS["Multiple Sclerosis<br/>Demyelinating Disease"]
    Alzheimer["Alzheimer's Disease<br/>Neurodegeneration"]
    Dementia["Dementia<br/>Cognitive Decline"]
    TBI["Traumatic Brain Injury<br/>Acute Injury"]
    
    Neuropathy["Neuropathy<br/>Nerve Damage"]
    Inflammation["Inflammation<br/>Immune Response"]
    Cancer["Cancer<br/>Malignancy"]
    
    BMAL1 --|"regulates"|--> VEGF
    HIF1A --|"regulates"|--> VEGF
    VEGF --|"promotes"|--> Angiogenesis
    bevacizumab --|"inhibits"|--> VEGF
    
    VEGF --|"activates"|--> ALS
    VEGF --|"expressed in"|--> MS
    VEGF --|"associated with"|--> Alzheimer
    VEGF --|"associated with"|--> Dementia
    VEGF --|"protective against"|--> TBI
    
    VEGF --|"expressed in"|--> Neuropathy
    VEGF --|"associated with"|--> Inflammation
    VEGF --|"activates"|--> Cancer
    
    Angiogenesis --|"supports"|--> TBI
    Inflammation --|"contributes to"|--> ALS
    Inflammation --|"contributes to"|--> MS
    
    style VEGF fill:#006494
    style BMAL1 fill:#4a1a6b
    style HIF1A fill:#4a1a6b
    style bevacizumab fill:#1b5e20
    style Angiogenesis fill:#1b5e20
    style TBI fill:#1b5e20
    style ALS fill:#ef5350
    style MS fill:#ef5350
    style Alzheimer fill:#ef5350
    style Dementia fill:#ef5350
    style Inflammation fill:#ef5350
    style Cancer fill:#ef5350
    style Neuropathy fill:#5d4400