gene 1,339 words KG: YAP1
Contents

YAP1 — Yes-Associated Protein 1

🧬 Gene Info
Gene SymbolYAP1
Full NameYes-Associated Protein 1
Chromosome11q22.1.
FunctionNeural development: YAP1 is essential for neural progenitor cell proliferation and maintenance of the neural stem cell pool during cortical development.
Primary ExpressionHippocampus, Cortex, Cerebellum, Substantia nigra (widespread)
Molecular Weight54 kDa
Exons9
PathwaysWnt, TGF-β, Notch
UniProt IDP46937
NCBI Gene ID10413
Ensembl IDENSG00000137693
OMIM606608
GeneCardsYAP1
Human Protein AtlasYAP1
TEAD-responsive elementsYAP1 expression is partially auto-regulated through TEAD-dependent transcription
Associated DiseasesAls, Cancer, Carcinoma, Tumor
InteractionsABCA1, Actin, AKT, ALS, AMPK, AND
SciDEX HypothesesMechanosensitive Epigenetic Transcription (MET)
KG Connections193 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

Mechanosensitive Epigenetic Transcription (MET)
Score: 0.00

Knowledge Graph (12 edges)

PTEN activates YAP1
YAP1 activates LOX
SPP1 associated_with YAP1
LOX activates YAP1
YAP1 activates PTEN
YAP1 activates GBM
TP53 therapeutic_target YAP1
YAP1 activates MYC
YAP1 activates MET
YAP1 therapeutic_target RB1

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