SciDEX — Wiki (46 pages)

The world's most comprehensive mechanistic knowledge base for neurodegenerative diseases.

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

Scientific World Model

What is the Scientific World Model?

📊 CSF Neurofilament Light Chain (NfL) in NeurodegenerationKG

📊 Cerebrospinal Fluid (CSF) Biomarkers OverviewKG

Cerebrospinal Fluid (CSF) Biomarkers in NeurodegenerationKG

💊 CSF1R Inhibitors for Parkinson's DiseaseKG

💊 CSF-1R InhibitorsKG

📊 NPTX1 and NPTXR CSF Markers Predict Alzheimer's Disease ProgressionKG

📊 Microglial Proteins in CSF Reveal AD Progression StatesKG

📊 CSF Biomarkers for Corticobasal Syndrome and Progressive Supranuclear PalsyKG

🏛️ University of California San Francisco

💊 Glymphatic and CSF Dynamics Enhancement for CBS/PSPKG

💊 CSF Dynamics and Glymphatic Therapy in CBS/PSPKG

📊 csf-pta181KG

💡 CSF1R-Targeted Microglia TherapyKG

GM-CSF Sargramostim Phase 2 (NCT04902703) - AD ImmunotherapyKG

🧪 Pexidartinib (PLX3397) CSF1R Inhibitor Parkinson's Disease Trial (NCT04888966)KG

💡 CSF1R Modulation Therapy: Microglia Reset ProtocolKG

📊 Phosphorylated Tau 217 (p-tau217)KG

👤 Bruce L. Miller — Director of UCSF Memory and Aging Center

💊 CSF1R Inhibitors for NeurodegenerationKG

🧬 CSF2RA — Colony Stimulating Factor 2 Receptor Alpha ChainKG

📊 CSF O-GlcNAc — Target Engagement Biomarker for OGA InhibitorsKG

🧬 csf1KG

📊 Total Tau (t-tau) in Cerebrospinal FluidKG

🔬 GM-CSF Receptor Alpha ChainKG

🔬 GM-CSF Receptor Common Beta ChainKG

💊 Section 126: Glymphatic System and CSF Dynamics in CBS/PSPKG

📊 Cerebrospinal Fluid (CSF) Biomarker PanelsKG

💊 CSF1R Modulation TherapyKG

📊 14-3-3 Proteins (CSF) - BiomarkerKG

🧬 CSF1R — Colony Stimulating Factor 1 ReceptorKG

📊 CSF and Blood Biomarkers in Progressive Supranuclear PalsyKG

🧬 CSF2 — Colony Stimulating Factor 2 (GM-CSF)KG

🧬 csf2rbKG

🔬 CSF1R Protein (Colony Stimulating Factor 1 Receptor)KG

📊 CSF Synaptic Biomarker Panel for Neurodegenerative DiseasesKG

⚙️ CSF and Blood Biomarkers in Progressive Supranuclear PalsyKG

📊 CSF Biomarker Comparison Across Neurodegenerative DiseasesKG

🧪 PLX5622 CSF1R Inhibitor Trial in Early Alzheimer's DiseaseKG

🏢 AD Glymphatic System and CSF Dynamics Therapy CompaniesKG

🧪 Sargramostim (GM-CSF) ALS TrialKG

🔧 Brain Waste Clearance and CSF Dynamics TherapiesKG

🧫 CSF Dynamic Biomarkers for Differential Diagnosis of NPH vs AD with Concomitant NPHKG

🧫 CSF Dynamic Biomarkers for Differential Diagnosis of NPH vs AD with Concomitant NPHKG

CSF Cytokine Profiles as Parkinson's Disease Biomarkers - Research GapKG

🔬 CSF1 ProteinKG

🔬 CSF1R-Inhibited MicrogliaKG