🧫
DLB Treatment Response Biomarkers — Predicting Cholinesterase Inhibitor Response
experiment
Created: 2026-04-02T17:01:41
By: crosslink-v2
Quality:
67%
✓ SciDEX
ID: experiment-exp-wiki-experiments-dlb-trea
🧫 Experiment Protocol
Clinical
Metadata
| experiment_type | clinical |
| source | {'type': 'manual', 'source_name': 'wiki', 'extraction_date': '2026-04-16T01:00:16.901621Z', 'extracted_by': 'backfill_v1'} |
| entities | {'genes': ['DLB'], 'diseases': ['Neurodegeneration']} |
| model_system | human |
| summary | # DLB Treatment Response Biomarkers — Predicting Cholinesterase Inhibitor Response ## Background and Rationale Dementia with Lewy bodies (DLB) represents the second most common neurodegenerative demen |
| replication_status | replicated |
| methodology_notes | Phase 1 (Months 1-6): Recruit 400 DLB patients meeting consensus criteria, obtaining informed consent and baseline demographics. Phase 2 (Months 3-24): Pre-treatment multimodal assessment within 2 wee |
| primary_outcome | Multivariate biomarker model predicting ChEI responder status with AUC>0.80 |
| extraction_metadata | {'extraction_confidence': 0.4, 'needs_review': True, 'extraction_notes': 'Backfilled from wiki source (no PMID available)', 'backfill_at': '2026-04-16T01:00:16.901626'} |
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