Singapore/Asia-Pacific Neurodegeneration Biotech Companies

Overview

Overview

The Asia-Pacific region (excluding Korea, China, Japan, India) has emerging biotechnology companies focused on developing treatments for neurodegenerative diseases. Singapore has positioned itself as a regional hub for biotech research, while Australia and New Zealand have active neuroscience research communities.

Singapore Companies

ES Revive Pte Ltd

ES Revive is a Singapore-based biotechnology company focused on developing treatments for age-related diseases, including neurodegenerative conditions.

• Headquarters: Singapore
• Focus: Alzheimer's disease, aging-related disorders
• Approach: Novel therapeutic modalities
• Status: Research and development

Virometix Pte Ltd

Virometix is a Singapore biotech focused on viral vector technologies for gene therapy.

• Headquarters: Singapore
• Focus: Gene therapy for neurological disorders
• Approach: Novel viral vectors
• Status: Preclinical

Mirxes Pte Ltd

Mirxes is a Singapore company focused on microRNA diagnostics and therapeutics.

• Headquarters: Singapore
• Focus: Alzheimer's disease diagnostics
• Approach: Biomarker development
• Status: Diagnostics development

Craytor Therapeutics

Craytor Therapeutics is a biotech company developing treatments for neurodegenerative diseases.

• Headquarters: Singapore
• Focus: Alzheimer's disease, Parkinson's disease
• Approach: Small molecule therapeutics
• Status: Research

Australian Companies

Activ8 Neuro

Activ8 Neuro is an Australian biotech focused on neurological disorders.

• Headquarters: Melbourne, Victoria
• Focus: Alzheimer's disease, Parkinson's disease
• Approach: Novel drug delivery
• Status: Preclinical

Neurizon Pty Ltd

Neurizon is an Australian company focused on neurodegenerative disease therapeutics.

• Headquarters: Sydney, New South Wales
• Focus: ALS, Alzheimer's disease
• Approach: Neuroprotective compounds
• Status: Research

Alterity Therapeutics (formerly Prana Biotechnology)

Alterity Therapeutics is an Australian biotech company developing treatments for neurodegenerative diseases.

• Headquarters: Melbourne, Victoria
• Focus: Parkinson's disease, Huntington's disease
• Key programs:
• PBT434 - Novel small molecule
• Status: Clinical trials

Actinogen Medical

Actinogen Medical is an Australian biotech focused on neurological disorders, developing treatments for Alzheimer's disease and major depressive disorder.

• Headquarters: Sydney, New South Wales
• Focus: Alzheimer's disease, cognitive impairment
• Key programs:
• Xanamem® (emestedastat) - 11β-HSD1 inhibitor targeting brain cortisol
• Status: Phase 2b/3 clinical trials (XanaMIA trial)
• Trial: XanaMIA Phase 2b/3 Alzheimer's disease trial enrollment closed; topline results expected November 2026
• Recent Updates (2025-2026): An independent Data Monitoring Committee conducted a positive interim analysis and recommended the trial continue without amendment, citing unblinded safety and efficacy data supporting completion. The company secured funding beyond the trial results following a $16.8 million placement and share purchase plan, plus $7.4 million in FY2025 R&D tax incentives from the Australian Tax Office. Additional programs target cognitive impairment in major depressive disorder and behavioral symptoms in Fragile X Syndrome.

Neurotech Australia

Neurotech is an Australian company developing neurotechnology devices.

• Headquarters: Brisbane, Queensland
• Focus: Parkinson's disease, movement disorders
• Approach: Deep brain stimulation technology
• Status: Medical devices

SYNthesis Research

SYNthesis is an Australian contract research organization with neuroscience expertise.

• Headquarters: Melbourne, Victoria
• Focus: CNS drug development
• Approach: Preclinical research services
• Status: Research services

Taiwanese Companies

TaiRx Inc.

TaiRx is a Taiwanese biotech developing anti-aging and neuroprotective therapeutics.

• Headquarters: Taipei, Taiwan
• Focus: Alzheimer's disease, aging
• Approach: Novel small molecules
• Status: Research

Scinexxic

Scinexxic is a Taiwanese company focused on neurological disease therapeutics.

• Headquarters: Taipei, Taiwan
• Focus: Alzheimer's disease, Parkinson's disease
• Approach: Protein aggregation inhibitors
• Status: Preclinical

New Zealand Companies

NZ Neuro Research

NZ Neuro Research is a New Zealand company focused on neurological disease research.

• Headquarters: Auckland
• Focus: Neurodegeneration research
• Approach: Academic partnerships
• Status: Research

Cognitive Health Research NZ

Cognitive Health Research is focused on Alzheimer's disease research in New Zealand.

• Headquarters: Wellington
• Focus: Alzheimer's disease
• Approach: Prevention strategies
• Status: Research

Academic and Research Institutions

Singapore

• Agency for Science, Technology and Research (A*STAR): Neuroscience research
• National Neuroscience Institute (NNI): Clinical research
• Duke-NUS Medical School: Neurodegeneration research

Australia

• Florey Institute of Neuroscience and Mental Health: Alzheimer's research
• Brain Institute (University of Queensland): Neurodegeneration
• Monash University: CNS research
• University of Sydney: Neuroscience research

Taiwan

• Academia Sinica: Neuroscience research
• National Taiwan University: Neurobiology research

Government Programs

Singapore

• National Research Foundation: Biotech funding
• EDB (Economic Development Board): Biotech incentives

Australia

• National Health and Medical Research Council (NHMRC): Research funding
• Medical Research Future Fund: Biomedical research

Clinical Trial Sites

Major pharmaceutical companies conduct clinical trials for neurodegenerative diseases at sites in:

• Singapore (National Neuroscience Institute)
• Australia (multiple sites)
• Taiwan (major medical centers)

See Also

• [Singapore/Asia-Pacific Neurodegeneration](/companies/singapore-asia-pacific-neurodegeneration)
• [Australian Neurodegeneration Biotech](/companies/australian-neurodegeneration-biotech)
• [Alzheimer's Disease](/diseases/alzheimers-disease)
• [Parkinson's Disease](/diseases/parkinsons-disease)

External Links

• [Alterity Therapeutics](https://alteritytx.com/)
• [Actinogen Medical](https://www.actinogen.com.au/)
• [A*STAR Singapore](https://www.astar.edu.sg/)
• [Florey Institute](https://www.florey.edu.au/)
• [ES Revive](https://www.esrevive.com/)
• [Queensland Brain Institute](https://qbi.uq.edu.au/)
• [AusBiotech](https://www.ausbiotech.org/)

References