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alpha-synuclein

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-proteins-alpha-synuclein
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ALPHASYNUCLEIN
Metadata
slugproteins-alpha-synuclein
entity_typeprotein
kg_node_idALPHASYNUCLEIN
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Linked Artifacts (162)
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mentions🧪Metabolic Reprogramming via Coordinated Multi-Gene CRISPR Ci65%
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mentions🧪Digital Twin-Guided Metabolic Reprogramming65%
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mentions🧪Multi-Modal CRISPR Platform for Simultaneous Editing and Mon65%
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mentions🧪Endothelial Glycocalyx Regeneration via Syndecan-1 Upregulat65%
mentions🧫Autophagy Enhancement Drug Screening for Neurodegeneration60%
mentions🧫Chaperone-Mediated Autophagy Dysfunction in PD - Experiment 60%
mentions🧫DLB Cognitive Fluctuation Mechanism Experiment60%
mentions🧫Tau Co-Pathology in DLB Clinical Heterogeneity60%
mentions🧫DLB Treatment Response Biomarkers — Predicting Cholinesteras60%
mentions🧫Mechanism: Selective Vulnerability of Dopaminergic Neurons i60%
mentions🧫Epigenetic Dysregulation Validation in Parkinson's Dise60%
mentions🧫Gap Junction Dysfunction Validation in Parkinson's Dise60%
mentions🧫Iron Dyshomeostasis in MSA Pathogenesis Experiment60%
mentions🧫Levodopa Response Determinants in PSP — Biomarker-Guided Pre60%
mentions🧫Macroautophagy Dysfunction in PD - Experiment Design60%
mentions🧫Validate Mitochondria-Lysosome Contact Site Dysfunction in P60%
mentions🧫Validation: Membrane-Nucleation in iPSC Neurons60%
mentions🧫Metabolic Syndrome-Parkinson's Disease Axis Clinical Tr60%
mentions🧫Experiment Design: Metal Ion-Synuclein-Mitochondria Axis in 60%
mentions🧫Experiment: Multi-Ethnic PD GWAS60%
mentions🧫Multiscale Computational Modeling of Protein Aggregation Kin60%
mentions🧫Non-Motor Symptom Progression in Parkinson's Disease — 60%
mentions🧫Oligodendrocyte-Myelin Dysfunction Validation in Parkinson&#60%
mentions🧫Peroxisome Dysfunction Validation in Parkinson's Diseas60%
mentions🧫Prion Strain Diversity and Selective Vulnerability in CJD60%
mentions🧫Purinergic Signaling Dysfunction Validation in Parkinson60%
mentions🧫Stress Granule Dysfunction Validation in Parkinson's Di60%
mentions🧫TREM2 Agonist Therapy for Parkinson's Disease — Experim60%
see_also📖Neurodegeneration60%
related🧪Netrin-1 Gradient Restoration58%
related🧪Smartphone-Detected Motor Variability Correction58%
related🧪Astrocytic Connexin-43 Upregulation Enhances Neuroprotective58%
related🧪SASP-Mediated Cholinergic Synapse Disruption58%
related🧪Noradrenergic-Tau Propagation Blockade58%
related🧪Quantum Coherence Disruption in Cellular Communication58%
related🧪Extracellular Vesicle Biogenesis Modulation58%
related🧪Glymphatic System-Enhanced Antibody Clearance Reversal58%
related🧪Bacterial Enzyme-Mediated Dopamine Precursor Synthesis58%
related🧪SASP-Driven Aquaporin-4 Dysregulation58%
related🧪Metabolic Reprogramming via Coordinated Multi-Gene CRISPR Ci58%
related🧪Synthetic Biology BBB Endothelial Cell Reprogramming58%
related🧪Enhancing Vagal Cholinergic Signaling to Restore Gut-Brain A58%
related🧪Digital Twin-Guided Metabolic Reprogramming58%
related🧪Circadian Clock-Autophagy Synchronization58%
related🧪Competitive APOE4 Domain Stabilization Peptides58%
related🧪Multi-Modal CRISPR Platform for Simultaneous Editing and Mon58%
related🧪Ephrin-B2/EphB4 Axis Manipulation58%
related🧪Phase-Separated Organelle Targeting58%
related🧪Cross-Seeding Prevention Strategy58%
related🧪Endothelial Glycocalyx Regeneration via Syndecan-1 Upregulat58%
related🧫Autophagy Enhancement Drug Screening for Neurodegeneration54%
related🧫Chaperone-Mediated Autophagy Dysfunction in PD - Experiment 54%
related🧫DLB Cognitive Fluctuation Mechanism Experiment54%
related🧫Tau Co-Pathology in DLB Clinical Heterogeneity54%
related🧫DLB Treatment Response Biomarkers — Predicting Cholinesteras54%
related🧫Mechanism: Selective Vulnerability of Dopaminergic Neurons i54%
related🧫Epigenetic Dysregulation Validation in Parkinson's Dise54%
related🧫Gap Junction Dysfunction Validation in Parkinson's Dise54%
related🧫Iron Dyshomeostasis in MSA Pathogenesis Experiment54%
related🧫Levodopa Response Determinants in PSP — Biomarker-Guided Pre54%
related🧫Macroautophagy Dysfunction in PD - Experiment Design54%
related🧫Validate Mitochondria-Lysosome Contact Site Dysfunction in P54%
related🧫Validation: Membrane-Nucleation in iPSC Neurons54%
related🧫Metabolic Syndrome-Parkinson's Disease Axis Clinical Tr54%
related🧫Experiment Design: Metal Ion-Synuclein-Mitochondria Axis in 54%
related🧫Experiment: Multi-Ethnic PD GWAS54%
related🧫Multiscale Computational Modeling of Protein Aggregation Kin54%
related🧫Non-Motor Symptom Progression in Parkinson's Disease — 54%
related🧫Oligodendrocyte-Myelin Dysfunction Validation in Parkinson&#54%
related🧫Peroxisome Dysfunction Validation in Parkinson's Diseas54%
related🧫Prion Strain Diversity and Selective Vulnerability in CJD54%
related🧫Purinergic Signaling Dysfunction Validation in Parkinson54%
related🧫Stress Granule Dysfunction Validation in Parkinson's Di54%
related🧫TREM2 Agonist Therapy for Parkinson's Disease — Experim54%
mentions🧪APOE-Dependent Autophagy Restoration50%
mentions🧪Gut Barrier Permeability-α-Synuclein Axis Modulation50%
mentions🧪Microbial Metabolite-Mediated α-Synuclein Disaggregation50%
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related🔬What are the mechanisms underlying 4r-tau strain-specific sp50%
related🔬What are the mechanisms underlying blood-brain barrier trans50%
related🔬What are the mechanisms underlying microglia-astrocyte cross50%
related🔬What are the mechanisms underlying apoe4 structural biology 50%
related🔬What are the mechanisms underlying digital biomarkers and ai50%
related🔬What are the mechanisms underlying senolytic therapy for age50%
related🔬What are the mechanisms underlying what are the mechanisms b50%
related🔬What are the mechanisms underlying sleep disruption as cause50%
related🔬What are the mechanisms underlying rna binding protein dysre50%
related🔬What are the mechanisms underlying mitochondrial transfer be50%
related🔬What are the mechanisms underlying perivascular spaces and g50%
related🔬Analyze circuit-level changes in neurodegeneration using All50%
related🔬Investigate prion-like spreading of tau pathology through co50%
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mentions🧫Alpha-Synuclein SAA Kinetics Study — Biological Staging Back40%
mentions🧫Alpha-Synuclein Aggregation Triggers — Sporadic PD Initiatio40%
mentions🧫Computational Modeling of Alpha-Synuclein Propagation in PD40%
mentions🧫Basic Mechanism: Membrane-Driven Alpha-Synuclein Nucleation40%
mentions🧫Alpha-Synuclein Seed Amplification Assay Validation40%
mentions🧫Alpha-Synuclein Spreading Mechanism — Prion-Like Propagation40%
mentions🧫Alpha-Synuclein Staging and Spreading in DLB — Spatial Propa40%
mentions🧫Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag40%
mentions🔬How to break the GBA-alpha-synuclein bidirectional loop for 40%
mentions🔬Analyze circuit-level changes in neurodegeneration using All40%
related🧪Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m40%
related🧪Gut Barrier Permeability-α-Synuclein Axis Modulation40%
related🧪Microbial Metabolite-Mediated α-Synuclein Disaggregation40%
related🧪Glymphatic System-Enhanced Antibody Clearance Reversal40%
related🧪SASP-Driven Aquaporin-4 Dysregulation40%
related🧪Aquaporin-4 Polarization Rescue40%
related🧪Circadian Rhythm Entrainment of Reactive Astrocytes40%
related🧪Temporal Decoupling via Circadian Clock Reset40%
related🧪Circadian Clock-Autophagy Synchronization40%
related🧪HSP70 Co-chaperone DNAJB6 Universal Cross-Seeding Inhibitor40%
related🧪GFAP-Positive Reactive Astrocyte Subtype Delineation40%
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related🧪TREM2-mediated microglial tau clearance enhancement40%
related🧪Cell-Type Specific TREM2 Upregulation in DAM Microglia40%
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