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LMNA Gene

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-genes-lmna

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Metadata

slug	genes-lmna
entity_type	gene
kg_node_id	LMNA

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Linked Artifacts (82)

mentions🧪APOE Isoform Conversion Therapy70%

mentions🧪Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides70%

related🧪APOE Isoform Conversion Therapy63%

related🧪Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides63%

see_also📖AMPK (AMP-Activated Protein Kinase)60%

see_also📖Packard Center for ALS Research60%

see_also📖Aging vs Neurodegeneration: Mechanistic Comparison Matrix60%

see_also📖ARHGEF2 Gene60%

see_also📖PPP1CC Gene - Protein Phosphatase 1 Catalytic Subunit Gamma60%

see_also📖Actin Cytoskeleton Dynamics in Neurodegeneration60%

see_also📖ATP1A1 Gene60%

see_also📖CREB3 Gene60%

see_also📖WWTR1 (TAZ) — WW Domain Containing Transcription Regulator 160%

see_also📖ATP1A1 Protein60%

see_also📖CTC1 Gene60%

see_also📖POLD160%

see_also📖SAMHD1 — SAM and HD Domain Containing Metal Dependent Hydrol60%

see_also📖POLD1 Protein60%

see_also📖Accelerating Medicines Partnership for Alzheimer's Dise60%

see_also📖a2m60%

see_also📖ABCD3 Gene60%

see_also📖ambra160%

see_also📖atp5f160%

see_also📖MYO5A — Myosin Va60%

see_also📖NBS1 (NBN)60%

see_also📖NEIL1 — Nei Endonuclease VIII-Like 160%

see_also📖POT1 Gene60%

see_also📖SDHB Gene60%

see_also📖TPM3 Gene60%

see_also📖WRN — Werner Syndrome RecQ Like Helicase60%

see_also📖Alzheimer Indonesia60%

see_also📖KCNH2 — Potassium Voltage-Gated Channel Subfamily H Member 260%

see_also📖LAMA2 — Laminin Subunit Alpha 260%

see_also📖PLN Gene60%

see_also📖TPM1 — Tropomyosin 160%

mentions🧪Glial Glycocalyx Remodeling Therapy50%

mentions🧪Synaptic Phosphatidylserine Masking via Annexin A1 Mimetics50%

mentions🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer50%

mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones50%

mentions🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction50%

mentions🧪Targeted APOE4-to-APOE3 Base Editing Therapy50%

mentions🧪Competitive APOE4 Domain Stabilization Peptides50%

mentions🧪APOE Isoform Expression Across Glial Subtypes50%

mentions🧪Palmitoylation-Targeted BACE1 Trafficking Disruptors50%

mentions🧪Complement C1q Mimetic Decoy Therapy50%

mentions🧪Complement C1q Subtype Switching50%

mentions🧪Complement C1QA Spatial Gradient in Cortical Layers50%

mentions🧪Temporal Decoupling via Circadian Clock Reset50%

mentions🧪Circadian Clock-Autophagy Synchronization50%

mentions🧪Stress Granule Phase Separation Modulators50%

mentions🧪Phase-Separated Organelle Targeting50%

mentions🧪RNA Granule Nucleation Site Modulation50%

mentions🧪Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem50%

mentions🧪Mitochondrial Transfer Pathway Enhancement50%

mentions🧪Nucleolar Stress Response Normalization50%

mentions🧪PARP1 Inhibition Therapy50%

mentions🧪Pericyte Contractility Reset via Selective PDGFR-β Agonism50%

mentions🧪Mitochondrial-Nuclear Epigenetic Cross-Talk Restoration50%

mentions🧪SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK50%

mentions🧪VCP-Mediated Autophagy Enhancement50%

mentions🧪APOE4-Selective Lipid Nanoemulsion Therapy50%

mentions🧪APOE-Dependent Autophagy Restoration50%

mentions🧪CYP46A1 Overexpression Gene Therapy50%

mentions🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th50%

related🔬What are the mechanisms underlying 4r-tau strain-specific sp50%

related🔬What are the mechanisms underlying neuroinflammation resolut50%

related🔬Investigate how lipid raft composition (cholesterol metaboli50%

related🔬What are the mechanisms underlying 4r-tau strain-specific sp50%

related🔬What are the mechanisms underlying neuroinflammation resolut50%

related🔬Investigate how lipid raft composition (cholesterol metaboli50%

related🔬Analyze circuit-level changes in neurodegeneration using All50%

related🧪APOE Isoform Conversion Therapy50%

related🔬What are the mechanisms underlying astrocyte reactivity subt50%

related🔬What are the mechanisms underlying microglia-astrocyte cross50%

related🔬What are the mechanisms underlying apoe4 structural biology 50%

related🔬What are the mechanisms underlying mechanistic role of apoe 50%

related🔬What are the mechanisms underlying rna binding protein dysre50%

mentions🔬Analyze circuit-level changes in neurodegeneration using All40%

related🧪CYP46A1 Overexpression Gene Therapy40%

related🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th40%

related🧪Glial Glycocalyx Remodeling Therapy40%

mentions🔬What are the mechanisms underlying 4r-tau strain-specific sp35%