gene

CDH23

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CDH23: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

35Connections
0Hypotheses
0Analyses
28Outgoing
7Incoming

Summary

Page for CDH23 Gene

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🧬 Gene Info
Gene SymbolCDH23
Full NameCadherin 23
Chromosome10q22.1
Functionencodes a member of the cadherin superfamily of calcium-dependent cell adhesion molecules.
Primary Expressionphotoreceptors:
Amino Acids654 aa
UniProt IDQ9Y6M7
NCBI Gene ID64061
Ensembl IDENSG00000107736
GeneCardsCDH23
Human Protein AtlasCDH23
Protein NameCadherin-23
Associated DiseasesALS, Inflammation, Neuroinflammation, Ptsd
KG Connections35 knowledge graph edges
DatabasesGeneCardsHPASTRING
🔮 Predicted Structure: CDH23 — AlphaFold Q9Y6M7 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (13)

Knowledge base pages for this entity

Canonical Page

CDH23 Gene

gene · 540 words

USH1G — USHER Syndrome 1G Protein (SANS)

gene · 3073 words

PCDH15 — Protocadherin 15

gene · 2425 words

USH1C Gene

gene · 2382 words

GPR98 Gene

gene · 1698 words

Usher Syndrome

disease · 1466 words

Pathway Diagram

graph TD
    CDH23["<b>CDH23</b>"]
    Als["Als"]
    CDH23 -->|"associated with"| Als
    Neuroinflammation["Neuroinflammation"]
    CDH23 -->|"associated with"| Neuroinflammation
    Alzheimer["Alzheimer"]
    CDH23 -->|"therapeutic target"| Alzheimer
    Aging["Aging"]
    CDH23 -->|"therapeutic target"| Aging
    Neuroinflammation["Neuroinflammation"]
    CDH23 -->|"therapeutic target"| Neuroinflammation
    ALS["ALS"]
    CDH23 -->|"associated with"| ALS
    Inflammation["Inflammation"]
    CDH23 -->|"associated with"| Inflammation
    GRM2["GRM2"]
    CDH23 -->|"associated with"| GRM2
    MITOCHONDRIA["MITOCHONDRIA"]
    CDH23 -->|"associated with"| MITOCHONDRIA
    HAPLN1["HAPLN1"]
    CDH23 -->|"associated with"| HAPLN1
    CCR5["CCR5"]
    CDH23 -->|"associated with"| CCR5
    P2RY12["P2RY12"]
    CDH23 -->|"associated with"| P2RY12
    AMYLOID["AMYLOID"]
    CDH23 -->|"therapeutic target"| AMYLOID
    APOPTOSIS["APOPTOSIS"]
    CDH23 -->|"therapeutic target"| APOPTOSIS
    ALZHEIMER["ALZHEIMER"]
    CDH23 -->|"therapeutic target"| ALZHEIMER
    AGING["AGING"]
    CDH23 -->|"therapeutic target"| AGING
    Oxidative_Stress["Oxidative Stress"]
    CDH23 -->|"therapeutic target"| Oxidative_Stress
    Apoptosis["Apoptosis"]
    CDH23 -->|"therapeutic target"| Apoptosis
    AND["AND"]
    CDH23 -->|"associated with"| AND
    Oxidative_Phosphorylation["Oxidative Phosphorylation"]
    CDH23 -->|"associated with"| Oxidative_Phosphorylation
    GENES["GENES"]
    GENES -->|"associated with"| CDH23
    NEUROINFLAMMATION["NEUROINFLAMMATION"]
    NEUROINFLAMMATION -->|"associated with"| CDH23
    P2RY12["P2RY12"]
    P2RY12 -->|"associated with"| CDH23
    CCR5["CCR5"]
    CCR5 -->|"associated with"| CDH23
    Amygdala["Amygdala"]
    CDH23 -->|"expressed in"| Amygdala
    Cortex["Cortex"]
    CDH23 -->|"expressed in"| Cortex
    Hippocampus["Hippocampus"]
    CDH23 -->|"expressed in"| Hippocampus
    Cerebellum["Cerebellum"]
    CDH23 -->|"expressed in"| Cerebellum
    neurodegeneration["neurodegeneration"]
    CDH23 -->|"implicated in"| neurodegeneration

Outgoing (28)

TargetRelationTypeStr
Ptsdassociated_withdisease0.65
Alsassociated_withdisease0.65
Neuroinflammationassociated_withdisease0.65
Alzheimertherapeutic_targetdisease0.65
Agingtherapeutic_targetdisease0.65

Incoming (7)

SourceRelationTypeStr
P2RY12associated_withgene0.60
CCR5associated_withgene0.60
HAPLN1associated_withgene0.60
GRM2associated_withgene0.60
GENESassociated_withgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found