concept

CYCLIN E1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CYCLIN E1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

34Connections
0Hypotheses
0Analyses
18Outgoing
16Incoming
0Experiments

No summary available yet. View on Wiki →

💡 Concept Info
NameCYCLIN E1
Key Genes/ProteinsBAX, P21, GENES, ROS, CDK2, CDK1
Related DiseasesAls, Glioblastoma
Related PathwaysBlood-Brain Barrier, Drug Resistance, Dna Repair, Apoptosis, Cell Cycle

Wiki Pages (2)

Knowledge base pages for this entity

Cyclin E2 (CCNE2) Protein

protein · 2832 words

E2F4 Gene

gene · 2417 words

Pathway Diagram

graph TD
    CYCLIN_E1["CYCLIN E1"]
    CYCLIN_E1 -->|"activates"| Als["Als"]
    CYCLIN_E1 -->|"expressed in"| Glioblastoma["Glioblastoma"]
    CYCLIN_E1 -->|"expressed in"| Blood_Brain_Barrier["Blood-Brain Barrier"]
    CYCLIN_E1 -->|"expressed in"| Drug_Resistance["Drug Resistance"]
    CYCLIN_E1 -->|"expressed in"| Dna_Repair["Dna Repair"]
    CYCLIN_E1 -->|"expressed in"| Apoptosis["Apoptosis"]
    CYCLIN_E1 -->|"activates"| Cell_Cycle["Cell Cycle"]
    CYCLIN_E1 -->|"expressed in"| BAX["BAX"]
    RB1["RB1"] -->|"regulates"| CYCLIN_E1
    BAX -->|"expressed in"| CYCLIN_E1
    ROS["ROS"] -->|"expressed in"| CYCLIN_E1
    APOPTOSIS["APOPTOSIS"] -->|"expressed in"| CYCLIN_E1
    CDK2["CDK2"] -->|"activates"| CYCLIN_E1
    EGFR["EGFR"] -->|"expressed in"| CYCLIN_E1
    GBM["GBM"] -->|"expressed in"| CYCLIN_E1
    GLIOBLASTOMA["GLIOBLASTOMA"] -->|"expressed in"| CYCLIN_E1

Outgoing (18)

TargetRelationTypeStr
Alsactivatesdisease0.65
Glioblastomaexpressed_indisease0.65
Blood-Brain Barrierexpressed_inpathway0.60
Drug Resistanceexpressed_inpathway0.60
Dna Repairexpressed_inpathway0.60

Incoming (16)

SourceRelationTypeStr
RB1regulatesgene0.70
BAXexpressed_ingene0.60
ROSexpressed_ingene0.60
APOPTOSISexpressed_ingene0.60
CDK2activatesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found