Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about foxp4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | FOXP4 |
| Full Name | Forkhead Box P4 |
| Chromosome | 6p12.1 |
| Protein Type | Transcription Factor |
| Function | is a member of the forkhead/winged-helix domain-containing transcription factor family, specifically the P subfamily of FOX proteins. |
| Primary Expression | Cortex, Hippocampus, Neurons |
| Molecular Weight | 75 kDa |
| Amino Acids | 680 aa |
| Exons | 17 |
| UniProt ID | Q9C0A1 |
| NCBI Gene ID | 22843 |
| Ensembl ID | ENSG00000106546 |
| OMIM | 609921 |
| GeneCards | FOXP4 |
| Human Protein Atlas | FOXP4 |
| Associated Diseases | Alzheimer's Disease, Parkinson's Disease, Autism |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
FOXP4["FOXP4"]
FOXP4 -->|"expressed in"| Diabetes["Diabetes"]
FOXP4 -->|"expressed in"| Cancer["Cancer"]
FOXP4 -->|"expressed in"| Carcinoma["Carcinoma"]
FOXP4 -->|"expressed in"| DIABETES_MELLITUS["DIABETES MELLITUS"]
FOXP4 -->|"expressed in"| Epigenetic["Epigenetic"]
FOXP4 -->|"expressed in"| Hedgehog["Hedgehog"]
FOXP4 -->|"expressed in"| CANCER["CANCER"]
FOXP4 -->|"implicated in"| neurodegeneration["neurodegeneration"]
SHH["SHH"] -->|"expressed in"| FOXP4
CANCER -->|"expressed in"| FOXP4
GENES["GENES"] -->|"expressed in"| FOXP4| Target | Relation | Type | Str |
|---|---|---|---|
| Diabetes | expressed_in | disease | 0.65 |
| Cancer | expressed_in | disease | 0.65 |
| Carcinoma | expressed_in | disease | 0.65 |
| FOXO4 | associated_with | gene | 0.60 |
| FOXO1 | associated_with | gene | 0.60 |
| FOXP2 | associated_with | gene | 0.60 |
| FOXG1 | associated_with | gene | 0.60 |
| FOXO6 | associated_with | gene | 0.60 |
| FOXM1 | associated_with | gene | 0.60 |
| DIABETES MELLITUS | expressed_in | gene | 0.60 |
| Epigenetic | expressed_in | pathway | 0.60 |
| Hedgehog | expressed_in | pathway | 0.60 |
| AND | associated_with | gene | 0.60 |
| CANCER | expressed_in | gene | 0.60 |
| benchmark_ot_ad_answer_key:FOXP4 | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| FOXA2 | associated_with | gene | 0.60 |
| FOXO6 | associated_with | gene | 0.60 |
| FOXO3 | associated_with | gene | 0.60 |
| FOXP3 | associated_with | gene | 0.60 |
| FOXG1 | associated_with | gene | 0.60 |
| SHH | expressed_in | gene | 0.60 |
| FOXP1 | associated_with | gene | 0.60 |
| FOXM1 | associated_with | gene | 0.60 |
| FOXO1 | associated_with | gene | 0.60 |
| FOXO4 | associated_with | gene | 0.60 |
| FOXP2 | associated_with | gene | 0.60 |
| FOXK2 | associated_with | gene | 0.60 |
| FOXD3 | associated_with | gene | 0.60 |
| FOXN3 | associated_with | gene | 0.60 |
| CANCER | expressed_in | gene | 0.60 |
| GENES | expressed_in | gene | 0.60 |
| benchmark_ot_ad_answer_key:FOXP4 | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||