FOXM1

Understanding Entity Pages

This page aggregates everything SciDEX knows about FOXM1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

FOXM1 is a gene implicated in neurodegeneration research. Key relationships include: therapeutic target, regulates, associated with. Associated with Als, Cancer, Carcinoma. Connected to 150 entities in the SciDEX knowledge graph.

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graph TD
    FOXM1["FOXM1"]
    FOXM1 -->|"regulates"| BUB1B["BUB1B"]
    FOXM1 -->|"downregulates"| IGF_1R_["IGF-1Rbeta"]
    FOXM1 -->|"target for"| Fibrosis["Fibrosis"]
    FOXM1 -->|"target for"| Hepatitis["Hepatitis"]
    FOXM1 -->|"target for"| Carcinoma["Carcinoma"]
    FOXM1 -->|"target for"| Cancer["Cancer"]
    FOXM1 -->|"target for"| Als["Als"]
    FOXM1 -->|"target for"| Inflammation["Inflammation"]
    FOXM1 -->|"target for"| Ms["Ms"]
    FOXM1 -->|"expressed in"| Diabetes["Diabetes"]
    SMC1A["SMC1A"] -->|"upregulates"| FOXM1
    HNRNPD["HNRNPD"] -->|"upregulates"| FOXM1
    NEDD4_1["NEDD4-1"] -->|"upregulates"| FOXM1
    YAP["YAP"] -->|"upregulates"| FOXM1
    TRIB3["TRIB3"] -->|"regulates"| FOXM1
    FGF20["FGF20"] -->|"target for"| FOXM1
    BRG1["BRG1"] -->|"regulates"| FOXM1
    NRCAM["NRCAM"] -->|"target for"| FOXM1
    NOTCH2["NOTCH2"] -->|"target for"| FOXM1