Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MYELODYSPLASTIC SYNDROME: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | MYELODYSPLASTIC SYNDROME |
Knowledge base pages for this entity
graph TD
MYELODYSPLASTIC_SYNDROME["MYELODYSPLASTIC SYNDROME"]
MYELODYSPLASTIC_SYNDROME -->|"activates"| Apoptosis["Apoptosis"]
MYELODYSPLASTIC_SYNDROME -->|"target for"| Nf__b["Nf-Kappab"]
MYELODYSPLASTIC_SYNDROME -->|"inhibits"| Angiogenesis["Angiogenesis"]
MYELODYSPLASTIC_SYNDROME -->|"treats"| Car_T["Car-T"]
MYELODYSPLASTIC_SYNDROME -->|"activates"| Breast_Cancer["Breast Cancer"]
MYELODYSPLASTIC_SYNDROME -->|"treats"| Inflammation["Inflammation"]
MYELODYSPLASTIC_SYNDROME -->|"inhibits"| Als["Als"]
GENES["GENES"] -->|"inhibits"| MYELODYSPLASTIC_SYNDROME
DNA["DNA"] -->|"activates"| MYELODYSPLASTIC_SYNDROME
CANCER["CANCER"] -->|"activates"| MYELODYSPLASTIC_SYNDROME
APOPTOSIS["APOPTOSIS"] -->|"activates"| MYELODYSPLASTIC_SYNDROME
CYTOKINES["CYTOKINES"] -->|"inhibits"| MYELODYSPLASTIC_SYNDROME
NF__B["NF-KappaB"] -->|"target for"| MYELODYSPLASTIC_SYNDROME| Target | Relation | Type | Str |
|---|---|---|---|
| Apoptosis | activates | pathway | 0.60 |
| Apoptosis | inhibits | pathway | 0.60 |
| Nf-Κb | therapeutic_target | pathway | 0.60 |
| Angiogenesis | inhibits | pathway | 0.60 |
| Car-T | treats | pathway | 0.60 |
| Breast Cancer | activates | disease | 0.55 |
| Inflammation | treats | disease | 0.55 |
| Als | inhibits | disease | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| GENES | inhibits | gene | 0.75 |
| TP53 | associated_with | gene | 0.65 |
| TP53 | treats | gene | 0.65 |
| MAX | inhibits | gene | 0.65 |
| MYC | inhibits | gene | 0.65 |
| DNA | activates | gene | 0.65 |
| CANCER | activates | gene | 0.65 |
| GENES | activates | gene | 0.65 |
| APOPTOSIS | activates | gene | 0.65 |
| Leukemia | associated_with | disease | 0.65 |
| CYTOKINES | inhibits | gene | 0.65 |
| APOPTOSIS | inhibits | gene | 0.65 |
| NF-ΚB | therapeutic_target | gene | 0.65 |
| Tumor | inhibits | disease | 0.65 |
| Cancer | inhibits | disease | 0.65 |
| INFLAMMATION | treats | gene | 0.65 |
| CANCER | inhibits | gene | 0.65 |
| Tumor | activates | disease | 0.55 |
| Cancer | activates | disease | 0.55 |
| Leukemia | therapeutic_target | disease | 0.55 |
| Myeloma | treats | disease | 0.55 |
| Leukemia | inhibits | disease | 0.55 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||