pathway

Car-T

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Car-T: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

86Connections

0Hypotheses

0Analyses

0Outgoing

50Incoming

No summary available yet. View on Wiki →

🔀 Pathway Info

Name	Car-T
Key Genes/Proteins	CANCER, BCL2, OVERVIEW, KRAS, PI3K, AKT
Related Diseases	Als, Tumor, Cancer, Leukemia, Colorectal Cancer

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    CAR_T["CAR-T"]
    Als["Als"] -->|"target for"| CAR_T
    CANCER["CANCER"] -->|"target for"| CAR_T
    Tumor["Tumor"] -->|"target for"| CAR_T
    Cancer["Cancer"] -->|"target for"| CAR_T
    Leukemia["Leukemia"] -->|"target for"| CAR_T
    BCL2["BCL2"] -->|"target for"| CAR_T
    OVERVIEW["OVERVIEW"] -->|"target for"| CAR_T
    KRAS["KRAS"] -->|"target for"| CAR_T

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (86)

Source	Relation	Type	Str
Als	therapeutic_target	disease	0.90
CANCER	therapeutic_target	gene	0.90
Tumor	therapeutic_target	disease	0.90
Cancer	therapeutic_target	disease	0.90
Leukemia	therapeutic_target	disease	0.80
BCL2	therapeutic_target	gene	0.70
OVERVIEW	therapeutic_target	gene	0.70
CANCER	regulates	gene	0.70
Cancer	regulates	disease	0.70
KRAS	therapeutic_target	gene	0.70
PI3K	therapeutic_target	gene	0.70
AKT	therapeutic_target	gene	0.70
Colorectal Cancer	therapeutic_target	disease	0.70
CD4	therapeutic_target	gene	0.60
CD8	therapeutic_target	gene	0.60
Infection	therapeutic_target	disease	0.60
RUNX2	regulates	gene	0.60
CYTOKINES	regulates	gene	0.60
Tumor	regulates	disease	0.60
Prostate Cancer	regulates	disease	0.60
Heart Failure	therapeutic_target	disease	0.60
Fibrosis	therapeutic_target	disease	0.60
Cardiac	therapeutic_target	disease	0.60
APOPTOSIS	activates	gene	0.60
BECN1	regulates	gene	0.60
RB1CC1	regulates	gene	0.60
TNF	activates	gene	0.60
AUTOPHAGY-RELATED GENES	regulates	gene	0.60
CD19	regulates	gene	0.60
TNFR1	activates	gene	0.60
STAT1	activates	gene	0.60
TNF-Α	activates	gene	0.60
GENES	regulates	gene	0.60
AUTOPHAGY	therapeutic_target	gene	0.60
IRF1	activates	gene	0.60
ATG3	regulates	gene	0.60
Tumor	associated_with	disease	0.60
Lymphoma	associated_with	disease	0.60
TP53	therapeutic_target	gene	0.60
EGFR	therapeutic_target	gene	0.60
VEGF	therapeutic_target	gene	0.60
RAS	therapeutic_target	gene	0.60
APC	therapeutic_target	gene	0.60
DNA	therapeutic_target	gene	0.60
GENE MUTATIONS	therapeutic_target	gene	0.60
Gastric Cancer	therapeutic_target	disease	0.60
INFLAMMATION	treats	gene	0.60
TP53	implicated_in	gene	0.60
Myeloma	associated_with	disease	0.60
Myelodysplastic Syndrome	treats	disease	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Car-T

Understanding Entity Pages

Wiki Pages (20)

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Therapeutic Modalities in Neurodegeneration

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fcgr2a-protein

SIGLEC9 — Sialic Acid Binding Ig-Like Lectin 9

Innovent Biologics

GPR89 (G Protein-Coupled Receptor 89 / GPRC5D)

Engineered iPSC-Microglia Cell Therapy for Neurodegeneration

Autoimmune Encephalitis Mechanisms

CAR-A Therapy — Chimeric Antigen Receptor Astrocytes for Alzheimer's Disease

TET2 Gene

Senescent Cell Clearance in Neurodegeneration

myasthenia-gravis

CSF1R Modulation Therapy: Microglia Reset Protocol