concept

SH3GL2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SH3GL2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

35Connections
0Hypotheses
0Analyses
22Outgoing
13Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameSH3GL2
Key Genes/ProteinsENDOPHILINPROTEIN, ROS, FLAVONOIDS, PARKINSON'S DISEASE, PARKINSON, PRKN
Related DiseasesParkinson, Als, Aging, Alzheimer, ALS

Wiki Pages (4)

Knowledge base pages for this entity

NRGN Gene - Neurogranin

gene · 1626 words

Endophilin Neurons

cell · 1024 words

Endophilin Protein

protein · 614 words

Intersectin Protein

protein · 605 words

Pathway Diagram

graph TD
    SH3GL2["SH3GL2"]
    SH3GL2 -->|"binds"| ENDOPHILINPROTEIN["ENDOPHILINPROTEIN"]
    SH3GL2 -->|"target for"| Als["Als"]
    SH3GL2 -->|"target for"| Aging["Aging"]
    SH3GL2 -->|"expressed in"| Alzheimer["Alzheimer"]
    SH3GL2 -->|"expressed in"| ALS["ALS"]
    SH3GL2 -->|"target for"| FLAVONOIDS["FLAVONOIDS"]
    SH3GL2 -->|"target for"| Oxidative_Stress["Oxidative Stress"]
    AGING["AGING"] -->|"target for"| SH3GL2
    OXIDATIVE_STRESS["OXIDATIVE STRESS"] -->|"target for"| SH3GL2
    LYSOSOME["LYSOSOME"] -->|"target for"| SH3GL2
    MITOCHONDRIAL_DYSFUNCTION["MITOCHONDRIAL DYSFUNCTION"] -->|"target for"| SH3GL2
    SYNAPSE["SYNAPSE"] -->|"target for"| SH3GL2
    ALZHEIMER["ALZHEIMER"] -->|"expressed in"| SH3GL2
    GENES["GENES"] -->|"expressed in"| SH3GL2
    MEF2C["MEF2C"] -->|"inhibits"| SH3GL2

Outgoing (22)

TargetRelationTypeStr
ENDOPHILINPROTEINbindsprotein0.80
Parkinsonassociated_withdisease0.65
Alstherapeutic_targetdisease0.65
Agingtherapeutic_targetdisease0.65
Alzheimerexpressed_indisease0.65

Incoming (13)

SourceRelationTypeStr
AGINGtherapeutic_targetgene0.60
OXIDATIVE STRESStherapeutic_targetgene0.60
LYSOSOMEtherapeutic_targetgene0.60
GENESassociated_withgene0.60
MITOCHONDRIAL DYSFUNCTIONtherapeutic_targetgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found