entity

synaptogenesis

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about synaptogenesis: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

22Connections

0Hypotheses

1Analyses

3Outgoing

19Incoming

0Experiments

1Debates

Wiki Pages (21)

Knowledge base pages for this entity

Canonical Page

Outgoing (3)

Target	Relation	Type	Str
NEURODEGENERATION	protects_against	disease	0.65
CORTEX	depleted_in	brain_region	0.55
CORTEX	associated_with	brain_region	0.45

Incoming (19)

Source	Relation	Type	Str
Calcium Homeostasis	regulates	process	0.95
RELN	regulates	entity	0.95
RLN	regulates	protein	0.95
BDNF	regulates	protein	0.90
CCL5	activates	protein	0.90
Calcium	regulates	compound	0.90
REELIN	regulates	protein	0.90
Reelin	regulates	protein	0.90
Obesity	associated_with	disease	0.90
RAC1	involved_in	protein	0.85
Stem Cell Therapy	promotes	drug	0.85
AUTOPHAGY	contributes_to	process	0.80
MICROGLIA	contributes_to	cell_type	0.80
MTOR	regulates	protein	0.70
BDNF	activates	protein	0.70
mTOR	regulates	protein	0.70
BIN1	activates	gene	0.65
SYN1	involved_in	gene	0.60
NEURON	implicated_in	cell_type	0.55

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (1)

Scientific analyses that reference this entity

How does SYNGAP1, a 'synaptic' protein, function in pre-synaptic radial glia cel

neurodevelopment | 2026-04-15 | 1 hypotheses Top: 0.576

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (1)

Multi-agent debates referencing this entity

This study reveals SYNGAP1 expression and function in radial glia before synapto

active · Rounds: 4 · Score: 1.00 · 2026-04-16

synaptogenesis

Understanding Entity Pages

Wiki Pages (21)

Synaptogenesis in Neurodegeneration

GRIA3 Gene

NTF4 Protein

CNTN5 — Contactin 5

ncam2

CNTN6 — Contactin 6

dendritic-spines

CNTN4 — Contactin 4

CNTN3 — Contactin 3

CREB Signaling in Neurodegeneration

MACF1 — Microtubule-actin crosslinking factor 1

NPAS3 Gene

IGF-1 Signaling Pathway in Neurodegeneration

Astrocytes

Kv7.3 Potassium Channel

CALM4 — Calmodulin 4

DLK2 — Delta-Like Non-Canonical Notch Ligand 2

SLC30A3 — Solute Carrier Family 30 Member 3 (ZnT3)

Amyloid Precursor Protein (APP)

Neurogenesis and Neurodegeneration

HRAS (Harvey Rat Sarcoma Viral Oncogene Homolog)