cell 854 words KG: GABA
Contents

Horizontal Limb of the Diagonal Band (HDB)

🧫 Cell Type Info
Cell TypeGABA
Key PathwaysGABAergic Signaling
Associated DiseasesALS, Als, Alzheimer, Alzheimer'S Disease, Amyotrophic Lateral Sclerosis, Ataxia
Related GenesATG, GABARAP, HDAC3, LC3, MAP1LC3B, MTOR
Linked Hypotheses220 hypotheses

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Knowledge Graph

Related Hypotheses (12)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.59
Purinergic Signaling Polarization Control
Score: 0.71
Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.67
APOE-Dependent Autophagy Restoration
Score: 0.85

Related Analyses (7)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Cell type vulnerability in Alzheimer's Disease (SEA-AD data
neurodegeneration · archived

Related Experiments (8)

Epigenetic Dysregulation in Huntington's Disease — Therapeut
validation · proposed · Score: 0.40
Microglial Contributions to Huntington's Disease Pathogenesi
validation · proposed · Score: 0.40
Trehalose-induced lysosomal changes and TFEB activation
exploratory · proposed · Score: 0.90
iPSC-NPC effects on astrocytes in vitro ICH model
exploratory · proposed · Score: 0.90
Trehalose-induced lysosomal membrane permeabilization and TF
exploratory · proposed · Score: 0.90

See Also (15)

BEACoN Study - Biomarker Exploration in Aging, Cognitio
clinical · Pages share 4 hypotheses
Synaptic Therapy Alzheimer's Research Trial (START): A
clinical · Pages share 4 hypotheses
p-Tau Biomarker in Immunoglobulin Light Chain and Trans
biomarker · Pages share 4 hypotheses
Synaptic Biomarkers in Neurodegeneration
biomarker · Pages share 4 hypotheses
Digital Therapeutic Platform for Swallowing and Droolin
clinical_trial · Pages share 4 hypotheses

Knowledge Graph (12 edges)

CRH regulates GABA
Pi3K activates GABA
TFEB activates GABA
EIF2A activates GABA
Autophagy activates GABA
STING1 activates GABA
RICTOR activates GABA
EIF2AK3 activates GABA
DDIT3 activates GABA
MLKL activates GABA

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