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cell 1,889 words KG: GABA 2026-03-24
kind:cell-typesection:cell-typesstate:published
Contents

Horizontal Limb of the Diagonal Band (HDB)

🧫 Cell Type Info
Cell TypeHorizontal Limb of the Diagonal Band (HDB)
Key PathwaysGABAergic Signaling
Associated DiseasesALS, Als, Alzheimer, Alzheimer'S Disease, Amyotrophic Lateral Sclerosis, Ataxia
Related GenesLC3, SLC6A13, AQP4
Linked Hypotheses122 hypotheses

Knowledge Graph

Related Hypotheses (14)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36Purinergic Signaling Polarization Control
Score: 0.55Mechanosensitive Ion Channel Reprogramming
Score: 0.51Lipid Droplet Dynamics as Phenotype Switches
Score: 0.46APOE-Dependent Autophagy Restoration
Score: 0.61

Related Analyses (7)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archivedBlood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archivedSenolytic therapy for age-related neurodegeneration
neurodegeneration · archivedWhat are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archivedCell type vulnerability in Alzheimer's Disease (SEA-AD data)
neurodegeneration · failed

Related Experiments (8)

Epigenetic Dysregulation in Huntington's Disease — Therapeut
validation · proposed · Score: 0.40Microglial Contributions to Huntington's Disease Pathogenesi
validation · proposed · Score: 0.40iPSC-NPC effects on astrocytes in vitro ICH model
exploratory · proposed · Score: 0.90Trehalose-induced lysosomal changes and TFEB activation
exploratory · proposed · Score: 0.90Trehalose-induced lysosomal membrane permeabilization and TF
exploratory · proposed · Score: 0.90

See Also (15)

ALS Therapeutic Landscape — Programs by Phase and Modal
disease · Pages share 4 hypothesesWnt/β-Catenin Signaling Pathway in Neurodegeneration
mechanism · Pages share 4 hypothesesWNK1-Bilirubin Signaling in Neuroinflammation and Neuro
mechanism · Pages share 4 hypothesesvip-vasoactive-intestinal-peptide-signaling-neurodegene
mechanism · Pages share 4 hypothesesVEGF Signaling and Cerebral Angiogenesis in Neurodegene
mechanism · Pages share 4 hypotheses

Knowledge Graph (12 edges)

GABA co_discussed JNK
GABA co_discussed LC3
GABA co_discussed LRRK2
GABA co_discussed MTOR
GABA co_discussed ULK1
GABA co_discussed HISTONE
GABA co_discussed ISCHEMIA
GABA co_discussed HTT
GABA co_discussed MITOCHONDRIA
GABA co_discussed MITOPHAGY
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